Griffin Susan O, Jones Kari, Crespin Matthew
Division of Oral Health, Centers for Disease Control, Atlanta, GA, USA.
J Public Health Dent. 2014 Summer;74(3):202-9. doi: 10.1111/jphd.12047. Epub 2014 Jan 15.
We describe a methodology for school-based sealant programs (SBSP) to estimate averted cavities, (i.e., difference in cavities without and with SBSP) over 9 years using a minimal data set.
A Markov model was used to estimate averted cavities. SBSP would input estimates of their annual attack rate (AR) and 1-year retention rate. The model estimated retention 2+ years after placement with a functional form obtained from the literature. Assuming a constant AR, SBSP can estimate their AR with child-level data collected prior to sealant placement on sealant presence, number of decayed/filled first molars, and age. We demonstrate the methodology with data from the Wisconsin SBSP. Finally, we examine how sensitive averted cavities obtained with this methodology is if an SBSP were to over or underestimate their AR or 1-year retention.
Demonstrating the methodology with estimated AR (= 7 percent) and 1-year retention (= 92 percent) from the Wisconsin SBSP data, we found that placing 31,324 sealants averted 10,718 cavities. Sensitivity analysis indicated that for any AR, the magnitude of the error (percent) in estimating averted cavities was always less than the magnitude of the error in specifying the AR and equal to the error in specifying the 1-year retention rate. We also found that estimates of averted cavities were more robust to misspecifications of AR for higher- versus lower-risk children.
With Excel (Microsoft Corporation, Redmond, WA, USA) spreadsheets available upon request, SBSP can use this methodology to generate reasonable estimates of their impact with a minimal data set.
我们描述了一种用于基于学校的窝沟封闭项目(SBSP)的方法,该方法使用最少的数据集来估计9年内避免的龋齿数量(即未实施SBSP和实施SBSP情况下龋齿数量的差异)。
使用马尔可夫模型来估计避免的龋齿数量。SBSP需输入其年度发病率(AR)和1年保留率的估计值。该模型通过从文献中获取的函数形式来估计放置后2年以上的保留情况。假设AR恒定,SBSP可以利用在放置窝沟封闭剂之前收集的儿童水平数据(关于窝沟封闭剂的存在情况、第一恒磨牙的龋坏/充填数量以及年龄)来估计其AR。我们用来自威斯康星州SBSP的数据演示了该方法。最后,我们研究了如果SBSP高估或低估其AR或1年保留率,用这种方法获得的避免龋齿数量的敏感性如何。
用威斯康星州SBSP数据估计的AR(=7%)和1年保留率(=92%)来演示该方法,我们发现放置31324颗窝沟封闭剂可避免10718颗龋齿。敏感性分析表明,对于任何AR,估计避免龋齿数量时的误差幅度(百分比)总是小于指定AR时的误差幅度,且等于指定1年保留率时的误差幅度。我们还发现,对于高风险和低风险儿童,避免龋齿数量的估计对AR的错误指定更具稳健性。
如有需要可提供Excel(美国华盛顿州雷德蒙德市微软公司)电子表格,SBSP可以使用这种方法,用最少的数据集对其影响做出合理估计。