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有抑郁病史的成年人的心理疼痛与静息状态心率变异性降低

Psychological pain and reduced resting-state heart rate variability in adults with a history of depression.

作者信息

Meerwijk Esther L, Chesla Catherine A, Weiss Sandra J

机构信息

Department of Community Health Systems, University of California, San Francisco, San Francisco, California, USA.

出版信息

Psychophysiology. 2014 Mar;51(3):247-56. doi: 10.1111/psyp.12175. Epub 2014 Jan 15.

DOI:10.1111/psyp.12175
PMID:24423213
Abstract

Psychological pain is a prominent symptom in people who experience depression, but its relation with physiological measures has not been explored. This study compared two measures of psychological pain, the Orbach & Mikulincer Mental Pain (OMMP) questionnaire and the Psychache Scale, for their relationship with resting-state heart rate variability (HRV) in 35 adults with a history of depression. Low-frequency HRV decreased significantly with increasing psychological pain, particularly in participants who did not use antidepressants, while the beat-to-beat fractal dimension decreased in participants who did use antidepressants. Neither heart rate nor high-frequency HRV was associated with psychological pain. These results suggest a state of arousal characterized by increased sympathetic activity. Results also indicate that the OMMP may be a more accurate measure of autonomic arousal associated with current psychological pain than the Psychache Scale.

摘要

心理疼痛是抑郁症患者的一个突出症状,但尚未探究其与生理指标之间的关系。本研究比较了两种心理疼痛测量方法,即奥尔巴赫和米库林纳心理疼痛(OMMP)问卷和心理痛苦量表,以探讨它们与35名有抑郁症病史的成年人静息心率变异性(HRV)之间的关系。随着心理疼痛加剧,低频HRV显著降低,尤其是未使用抗抑郁药的参与者,而逐搏分形维数在使用抗抑郁药的参与者中降低。心率和高频HRV均与心理疼痛无关。这些结果表明存在一种以交感神经活动增加为特征的唤醒状态。结果还表明,与心理痛苦量表相比,OMMP可能是一种更准确测量与当前心理疼痛相关的自主神经唤醒的方法。

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