巴西患者大肠埃希菌尿液分离株中的抗生素耐药性及sul2基因检测
Antibiotic resistance and detection of the sul2 gene in urinary isolates of Escherichia coli in patients from Brazil.
作者信息
Teichmann Aline, Agra Homero Neto de Cunha, Nunes Luciana de Souza, da Rocha Marion Pereira, Renner Jane Dagmar Pollo, Possuelo Lia Gonçalves, Carneiro Marcelo, Rieger Alexandre, Benitez Lisianne Brittes, Valim Andréia Rosane de Moura
机构信息
Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
出版信息
J Infect Dev Ctries. 2014 Jan 15;8(1):39-43. doi: 10.3855/jidc.3380.
INTRODUCTION
The present study aimed to assess the antibiotic resistance profiles and detect the presence of the sul2 gene in sulfamethoxazole-susceptible and resistant isolates of Escherichia coli obtained from outpatients and inpatients with urinary tract infections.
METHODOLOGY
The resistance profiles of 739 strains were assessed and the presence of the sul2 gene in 100 isolates was tested.
RESULTS
The antibiotics with the highest resistance rates were ampicillin (57.4%) and trimethoprim-sulfamethoxazole (44.7%). The presence of the gene sul2 was detected in 66.7% of outpatient samples and 67.9% of inpatient samples.
CONCLUSIONS
Our results demonstrate that E. coli isolates exhibit high resistance to various classes of antibiotics, highlighting the need for developing strategies to help in prescribing antibiotics.
引言
本研究旨在评估从尿路感染门诊和住院患者中分离出的对磺胺甲恶唑敏感和耐药的大肠杆菌菌株的抗生素耐药谱，并检测sul2基因的存在情况。
方法
评估了739株菌株的耐药谱，并检测了100株分离株中sul2基因的存在情况。
结果
耐药率最高的抗生素是氨苄西林（57.4%）和甲氧苄啶-磺胺甲恶唑（44.7%）。在66.7%的门诊样本和67.9%的住院样本中检测到sul2基因。
结论
我们的结果表明，大肠杆菌分离株对各类抗生素表现出高度耐药性，凸显了制定有助于合理使用抗生素策略的必要性。
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