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[美沙酮维持治疗门诊中接受抗逆转录病毒治疗的HIV感染注射吸毒者的现状及相关影响因素]

[Current situation related to antiretroviral therapy and related influential factors on HIV infected injection drug users in the methadone maintenance treatment clinics].

作者信息

Cheng Xiao-Qing, Pang Lin, Cao Xiao-Bin, Wang Chang-He, Luo Wei, Zhang Bo, Wang Hua, Li Rong-Jian, Rou Ke-Ming, Wu Zun-You

机构信息

National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Bejing 102206, China.

Yunnan Institute for Drug Abuse.

出版信息

Zhonghua Liu Xing Bing Xue Za Zhi. 2013 Aug;34(8):792-5.

PMID:24423765
Abstract

OBJECTIVE

To find out the current coverage of antiretroviral therapy (ART) among HIV positive subjects and to identify the major influential factors associated with the participation in ART among them.

METHODS

291 HIV positive subjects from 6 methadone maintenance treatment (MMT) clinics in Guangxi and Yunnan province were surveyed by questionnaires.

RESULTS

217 males (74.6%) and 74 females (25.4%) were under investigation, with the average age of 38.4 +/- 5.9. Most of them received less than senior high school education, married and unemployed. Results from the single factor logistic regression analysis showed that: working status, living alone, self-reported history of drinking alcohol in the last month, negative attitude towards MMT among family members,poor self-reported compliance to MMT in the last month,lack of incentives in the MMT clinics, reluctance on disclosure of their own HIV status, good self-perception on their health status, lack of communication on ART related topics among family members in the last 6 months, lack of correct attitude and knowledge on ART etc. appeared as the main factors that influencing the participation in ART program among the patients. Data from the multivariate logistic regression analysis showed that factors as: living alone, unwilling to tell others about the status of HIV infection, poor self-perception on HIV infection, lack of discussion of ART related topics within family members in the last 6 months and poor awareness towards ART among the family members etc., were associated with the low participation rate of ART. Conclusion Strengthening the publicity and education programs on HIV positive patients and their family members at the MMT clinics seemed to be effective in extending the ART coverage. Attention should also be paid to increase the family support to the patients.

摘要

目的

了解HIV阳性患者中抗逆转录病毒疗法(ART)的当前覆盖情况,并确定影响他们参与ART的主要相关因素。

方法

通过问卷调查对来自广西和云南省6家美沙酮维持治疗(MMT)诊所的291名HIV阳性患者进行了调查。

结果

接受调查的有217名男性(74.6%)和74名女性(25.4%),平均年龄为38.4±5.9岁。他们大多接受的教育程度低于高中,已婚且失业。单因素逻辑回归分析结果显示:工作状态、独居、自述上个月有饮酒史、家庭成员对MMT持消极态度、自述上个月MMT依从性差、MMT诊所缺乏激励措施、不愿披露自己的HIV感染状况、对自身健康状况自我感觉良好、过去6个月家庭成员之间缺乏关于ART相关话题的交流、对ART缺乏正确的态度和知识等,是影响患者参与ART项目的主要因素。多因素逻辑回归分析数据显示:独居、不愿告诉他人HIV感染状况、对HIV感染自我感觉不佳、过去6个月家庭成员之间缺乏对ART相关话题的讨论以及家庭成员对ART的知晓率低等因素,与ART参与率低有关。结论:加强MMT诊所针对HIV阳性患者及其家庭成员的宣传教育项目,似乎有助于扩大ART的覆盖范围。还应注意增加家庭对患者的支持。

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