大脑后动脉偏侧性对大脑中动脉闭塞的预后影响
[Prognostic effect of posterior cerebral artery laterality on middle cerebral artery occlusion].
作者信息
Chen Xiang-liang, Xiong Yun-yun, Li Yong-kun, Ma Min-min, Liu Xin-feng
机构信息
Department of Neurology, Jinling Hospital, School of Medicine, Nanjing University, Nanjing 210002, China.
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出版信息
Zhonghua Yi Xue Za Zhi. 2013 Nov 19;93(43):3428-32.
OBJECTIVE
To explore the prognostic value of posterior cerebral artery (PCA) laterality in patients with symptomatic middle cerebral artery (MCA) occlusion on standard medical therapy.
METHODS
Forty consecutive patients with first onset isolated atherosclerotic occlusion in M1 segment of MCA received medication from June 2009 to March 2013. All patients underwent magnetic resonance angiography (MRA) for assessment of PCA laterality. Clinical data and modified Rankin Scale (mRS) at 3 months were compared between PCA positive and negative patients. Retrospective analysis was performed on their clinical and imaging data.
RESULTS
Among them, 20 patients (50%) showed PCA laterality on MRA and 32 patients (80%) completed a 3-month follow-up. No significant difference existed between PCA laterality positive and negative groups in a favorable outcome of mRS = 0-1 at 3 months (P = 0.433).
CONCLUSION
The presence of PCA laterality showed no prognostic effect on patients with symptomatic MCA occlusion on standard medical therapy.
目的
探讨大脑后动脉（PCA）偏侧性对接受标准药物治疗的症状性大脑中动脉（MCA）闭塞患者的预后价值。
方法
2009年6月至2013年3月，连续40例首次发生孤立性MCA M1段动脉粥样硬化闭塞的患者接受药物治疗。所有患者均接受磁共振血管造影（MRA）以评估PCA偏侧性。比较PCA阳性和阴性患者的临床资料及3个月时的改良Rankin量表（mRS）评分。对其临床和影像资料进行回顾性分析。
结果
其中，20例患者（50%）MRA显示PCA偏侧性，32例患者（80%）完成了3个月的随访。3个月时mRS = 0 - 1的良好预后在PCA偏侧性阳性和阴性组之间无显著差异（P = 0.433）。
结论
PCA偏侧性对接受标准药物治疗的症状性MCA闭塞患者的预后无影响。
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