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眼球测试的准确性如何?:心脏手术后估计死亡风险时医生主观评估与统计方法的比较

How accurate is the eyeball test?: a comparison of physician's subjective assessment versus statistical methods in estimating mortality risk after cardiac surgery.

作者信息

Jain Renuka, Duval Sue, Adabag Selcuk

机构信息

Lillehei Heart Institute and Cardiovascular Division, University of Minnesota Medical School, Minneapolis, MN.

出版信息

Circ Cardiovasc Qual Outcomes. 2014 Jan;7(1):151-6. doi: 10.1161/CIRCOUTCOMES.113.000329. Epub 2014 Jan 14.

Abstract

BACKGROUND

In the era of increasing percutaneous treatment options for heart disease, the estimation of surgical risk has become a key factor in selecting optimal treatment strategies. Surgical risk has historically been estimated by physician's subjective assessment and more recently by statistical risk estimates.

METHODS AND RESULTS

We studied 5099 consecutive patients who underwent cardiac surgery at Minneapolis Veterans Affairs Medical Center between 1993 and 2010. Operative mortality risk was estimated statistically by the Veterans Affairs mortality risk estimate and subjectively by cardiac surgeons before surgery. Observed mortality rate was 3.3% (168 deaths) at 1 month, 7.1% (360 deaths) at 1 year, and 18.5% (942 deaths) at 5 years after surgery. Physician's risk estimate (mean [SD], 5.6% [4.4]) and statistical risk estimate (4.3% [5.1]) had modest correlation (c-index, 0.56; P<0.001). Both methods modestly overestimated operative mortality risk. Statistical risk estimate was significantly better than physician's risk estimate in separating patients who died from those who survived at 30 days (c-index, 0.78 versus 0.73; P=0.003), at 1 year (c-index, 0.72 versus 0.61; P<0.001), and at 5 years (c-index, 0.72 versus 0.64; P<0.001) after surgery. Physician's risk estimate was higher than statistical risk estimate in all subgroups except high-risk patients.

CONCLUSIONS

In patients undergoing cardiac surgery, statistical risk estimate is a better method to predict operative and long-term mortality compared with physician's subjective risk estimate. However, both methods modestly overestimate actual operative mortality risk.

摘要

背景

在心脏病经皮治疗选择日益增多的时代,手术风险评估已成为选择最佳治疗策略的关键因素。过去,手术风险是通过医生的主观评估来估计的,最近则通过统计风险估计来进行评估。

方法与结果

我们研究了1993年至2010年间在明尼阿波利斯退伍军人事务医疗中心接受心脏手术的5099例连续患者。手术死亡率风险通过退伍军人事务部死亡率风险估计进行统计评估,并由心脏外科医生在手术前进行主观评估。术后1个月观察到的死亡率为3.3%(168例死亡),1年时为7.1%(360例死亡),5年时为18.5%(942例死亡)。医生的风险估计(均值[标准差],5.6%[4.4])与统计风险估计(4.3%[5.1])具有适度相关性(c指数,0.56;P<0.001)。两种方法均适度高估了手术死亡率风险。在区分术后30天、第1年和第5年死亡患者与存活患者方面,统计风险估计显著优于医生的风险估计(c指数分别为0.78对0.73;P=0.003、0.72对0.61;P<0.001、0.72对0.64;P<0.001)。除高危患者外,在所有亚组中医生的风险估计均高于统计风险估计。

结论

在接受心脏手术的患者中,与医生的主观风险估计相比,统计风险估计是预测手术和长期死亡率的更好方法。然而,两种方法均适度高估了实际手术死亡率风险。

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