急性早幼粒细胞白血病在年轻人中表现为缺血性中风。
Acute promyelocytic leukemia presenting as ischemic stroke in young.
作者信息
Kapoor Rajan, Pati H P, Gupta Sanjeev Kumar, Gupta Nitin
机构信息
Department of Hematology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi India.
出版信息
Indian J Hematol Blood Transfus. 2013 Jun;29(2):93-5. doi: 10.1007/s12288-012-0145-z. Epub 2012 Feb 1.
Abstract
Coagulopathy in acute promyelocytic leukemia (APL) is a very complex disorder and is believed to result from interplay of various factors. Usually patients present with bleeding tendencies which can be life threatening. However, a few present with thromboses. Here, we report a young male with APL who presented with ischemic stroke in young.
摘要
急性早幼粒细胞白血病（APL）中的凝血功能障碍是一种非常复杂的病症，被认为是多种因素相互作用的结果。通常患者会出现可能危及生命的出血倾向。然而，少数患者会出现血栓形成。在此，我们报告一名患有APL的年轻男性，其在年轻时发生了缺血性中风。
相似文献
1
Acute promyelocytic leukemia presenting as ischemic stroke in young.
Indian J Hematol Blood Transfus. 2013 Jun;29(2):93-5. doi: 10.1007/s12288-012-0145-z. Epub 2012 Feb 1.
2
Transient ischemic attack as an unusual initial manifestation of acute promyelocytic leukemia.
Int J Hematol. 2016 Jul;104(1):134-8. doi: 10.1007/s12185-016-1982-6. Epub 2016 Mar 16.
3
Case Report: ANXA2 Associated Life-Threatening Coagulopathy With Hyperfibrinolysis in a Patient With Non-APL Acute Myeloid Leukemia.
Front Oncol. 2021 Apr 15;11:666014. doi: 10.3389/fonc.2021.666014. eCollection 2021.
4
Advances in the management of coagulopathy in acute promyelocytic leukemia.
Thromb Res. 2020 Jul;191 Suppl 1:S63-S67. doi: 10.1016/S0049-3848(20)30399-6.
5
A case of ischemic stroke in acute promyelocytic leukemia at initial presentation. Relevance of all-trans retinoic acid treatment.
Cardiovasc Hematol Disord Drug Targets. 2010 Mar;10(1):1-6. doi: 10.2174/187152910790780069.
6
Increased promyelocytic-derived microparticles: a novel potential factor for coagulopathy in acute promyelocytic leukemia.
Ann Hematol. 2013 May;92(5):645-52. doi: 10.1007/s00277-013-1676-6. Epub 2013 Jan 24.
7
Massive Pulmonary Embolism at the Onset of Acute Promyelocytic Leukemia.
Mediterr J Hematol Infect Dis. 2016 Jul 1;8(1):e2016027. doi: 10.4084/MJHID.2016.027. eCollection 2016.
8
Thrombosis in acute promyelocytic leukemia.
Thromb Res. 2013 Apr;131(4):281-9. doi: 10.1016/j.thromres.2012.11.024. Epub 2012 Dec 23.
9
Acute promyelocytic leukemia presenting with features of metastatic osseous disease.
Leuk Res Rep. 2018 Feb 12;9:36-37. doi: 10.1016/j.lrr.2018.02.003. eCollection 2018.
10
Open issues on bleeding and thrombosis in acute promyelocytic leukemia.
Thromb Res. 2010 Apr;125 Suppl 2:S51-4. doi: 10.1016/S0049-3848(10)70013-X.
引用本文的文献
1
Ischemic stroke as the initial presentation in acute myeloid leukemia vs. myelodysplastic syndrome: a case report and literature review with pathophysiological and clinical exploration.
Neurol Sci. 2024 Jul;45(7):3297-3304. doi: 10.1007/s10072-024-07367-1. Epub 2024 Feb 14.
2
Acute promyelocytic leukemia presenting as recurrent venous and arterial thrombotic events: a case report and review of the literature.
J Community Hosp Intern Med Perspect. 2021 Nov 15;11(6):832-838. doi: 10.1080/20009666.2021.1973657. eCollection 2021.
3
Unusual Presentation of Acute Leukaemia: A Tripod of Cases.
J Clin Diagn Res. 2016 Oct;10(10):ED04-ED08. doi: 10.7860/JCDR/2016/21472.8715. Epub 2016 Oct 1.
本文引用的文献
1
Acute Budd-Chiari syndrome as an initial presentation of acute promyelocytic leukemia.
J Cancer Res Ther. 2010 Oct-Dec;6(4):567-9. doi: 10.4103/0973-1482.77077.
2
Occurrence of thrombotic events in acute promyelocytic leukemia correlates with consistent immunophenotypic and molecular features.
Leukemia. 2007 Jan;21(1):79-83. doi: 10.1038/sj.leu.2404377. Epub 2006 Aug 24.
3
Simultaneous presentation of acute myocardial infarction and acute promyelocytic leukemia.
Ann Hematol. 2006 Jun;85(6):409-10. doi: 10.1007/s00277-006-0106-4. Epub 2006 Mar 24.
4
Extensive splenic infarction, deep vein thrombosis and pulmonary emboli complicating induction therapy with all-trans-retinoic acid (ATRA) for acute promyelocytic leukemia.
Leuk Lymphoma. 2003 Aug;44(8):1433-7. doi: 10.1080/1042819031000076963.
5
Coagulopathy of acute promyelocytic leukemia.
Acta Haematol. 2001;106(1-2):43-51. doi: 10.1159/000046588.
6
Intraventricular thrombosis during all-trans retinoic acid treatment in acute promyelocytic leukemia.
Leukemia. 2001 Aug;15(8):1311-3. doi: 10.1038/sj.leu.2402156.
7
Reversible portal vein thrombosis complicating induction therapy of acute promyelocytic leukemia.
Thromb Res. 2001 Jan 15;101(2):101-3. doi: 10.1016/s0049-3848(00)00371-6.
8
All-trans retinoic acid (ATRA) and tranexamic acid: a potentially fatal combination in acute promyelocytic leukaemia.
Br J Haematol. 2000 Sep;110(4):1010-2. doi: 10.1046/j.1365-2141.2000.02270-8.x.
9
Annexin II and bleeding in acute promyelocytic leukemia.
N Engl J Med. 1999 Apr 1;340(13):994-1004. doi: 10.1056/NEJM199904013401303.
10
Coronaric thrombotic events in acute promyelocytic leukemia during all-trans retinoic acid treatment: a role for adhesion molecules overexpression?
Leukemia. 1999 Feb;13(2):312-3. doi: 10.1038/sj.leu.2401273.
Zotero 插件