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印度锡金邦非黑色素瘤皮肤癌模式:一项为期3年的临床病理回顾

Pattern of Nonmelanoma Skin Cancers in Sikkim, India: A 3-year Clinicopathological Review.

作者信息

Baruah Binayak, Sengupta Subhabrata, Kesari Santosh P, Ilapakurty Bhargaw

机构信息

Department of ENT, Sikkim Manipal Institute of Medical Sciences, 5th mile, Tadong, Gangtok, 737 102 Sikkim India.

出版信息

Indian J Otolaryngol Head Neck Surg. 2013 Jul;65(Suppl 1):160-2. doi: 10.1007/s12070-013-0652-8. Epub 2013 Apr 13.

Abstract

Basal cell carcinoma (BCC) and Squamous cell carcinoma (SCC), in combination, are referred to as Nonmelanoma skin cancers (NMSCs). NMSC has not been extensively studied in the population of the North eastern India as it has been done in the rest of India. This study was performed to understand the pattern of NMSCs in head and neck region in Sikkimese population. The present study is a retrospective analysis of NMSC of head and neck region that presented to the Department of ENT, Sikkim Manipal Institute of Medical sciences (SMIMS), a tertiary care center in Gangtok, Sikkim from July 2009 to July 2012. They were reviewed according to age, gender, site of involvement and histological types. Of the thirty-seven cases of NMSC analyzed during the 3 year study period, 24 cases were SCC and 13 cases were BCC. The most common age group for SCC was 40-50 years and BCC was 61-70 years. The most common site for both SCC and BCC was the upper lip. For SCC, the most common histologically type was well-differentiated and for BCC, it was the solid type. NMSCs comprise a small but significant proportion of all skin cancer patients in the world. SCC is the commonest variety unlike in western countries. The importance of understanding the risk factors as well as studying the frequency of histopathological patterns can help in the overall prognostic outlook for patients and also in planning an effective management.

摘要

基底细胞癌(BCC)和鳞状细胞癌(SCC)合称为非黑色素瘤皮肤癌(NMSC)。与印度其他地区相比,印度东北部人群中的NMSC尚未得到广泛研究。本研究旨在了解锡金人群头颈部NMSC的发病模式。本研究是对2009年7月至2012年7月期间在锡金甘托克的三级护理中心锡金马尼帕尔医学科学研究所(SMIMS)耳鼻喉科就诊的头颈部NMSC进行的回顾性分析。根据年龄、性别、受累部位和组织学类型对其进行了评估。在为期3年的研究期间分析的37例NMSC病例中,24例为SCC,13例为BCC。SCC最常见的年龄组为40 - 50岁,BCC为61 - 70岁。SCC和BCC最常见的部位均为上唇。SCC最常见的组织学类型为高分化型,BCC为实体型。NMSC在全球所有皮肤癌患者中占比虽小但意义重大。与西方国家不同,SCC是最常见的类型。了解危险因素以及研究组织病理学模式的频率对于患者的总体预后以及规划有效的治疗方案具有重要意义。

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