Department of Pathology, Manipal Teaching Hospital, Pokhara, Nepal.
JNMA J Nepal Med Assoc. 2021 Nov 15;59(243):1106-1110. doi: 10.31729/jnma.6086.
Skin tumors are relatively uncommon malignancies worldwide, but its incidence has been progressively increased over the last few decades. Skin tumor belongs to a diverse group of neoplasms arising from the epidermis, adnexal structures and dermis rendering the classification difficult. The study aims to find out the prevalence of benign skin neoplasm among the histopathological specimens of skin neoplasm of a teaching hospital.
A descriptive cross-sectional study among the hospital records of histopathological samples of skin neoplasm in the Department of Pathology of a tertiary care center from January 2017 to December 2020. Ethical approval was taken from the Institutional Review Committee (Ref: MEMG/IRC/427/GA). Convenient sampling was done. Data were entered in Microsoft Excel and analyzed using Statistical Package for the Social Sciences version 21 software. Point estimate at 95% Confidence Interval was calculated with frequency and descriptive statistics.
Out of total skin neoplasm samples, 121 (57.34%) (50.67-64.01 at 95% Confidence Interval) benign skin neoplasms were present. Among them, the majority were keratinocytic tumor 81 (66.9%) followed by skin appendageal 23 (19.0%) and melanocytic tumors 17 (14.0%). Acrochordan 18 (14.9%) and pilomatricoma 12 (9.9%) were the predominant keratinocytic and appendageal neoplasms respectively. Most of the cases occurred in head and neck region 64 (52.9%).
The study concluded that the prevalence of benign skin neoplasm was slightly lower compared to the other studies. Most of the benign skin neoplasms were keratinocytic tumors followed by appendageal and melanocytic tumors. Acrochordan was the commonest benign keratinocytic tumor.
皮肤肿瘤是全球相对罕见的恶性肿瘤,但在过去几十年中其发病率呈逐渐上升趋势。皮肤肿瘤属于一组起源于表皮、附属结构和真皮的不同类型的肿瘤,分类较为困难。本研究旨在探讨某教学医院皮肤肿瘤组织病理学标本中良性皮肤肿瘤的患病率。
对某三级保健中心病理科 2017 年 1 月至 2020 年 12 月期间的皮肤肿瘤组织病理学样本的医院记录进行描述性横断面研究。本研究已获得机构审查委员会的伦理批准(REF:MEMG/IRC/427/GA)。采用方便抽样法。数据输入 Microsoft Excel 并使用社会科学统计软件包(SPSS)版本 21 进行分析。使用频率和描述性统计计算 95%置信区间的点估计值。
在所有皮肤肿瘤样本中,良性皮肤肿瘤 121 例(57.34%)(95%置信区间为 50.67%-64.01%)。其中,角化细胞肿瘤 81 例(66.9%)最多,其次是皮肤附属器肿瘤 23 例(19.0%)和黑素细胞肿瘤 17 例(14.0%)。软纤维瘤 18 例(14.9%)和毛母细胞瘤 12 例(9.9%)分别为最常见的角化细胞和附属器肿瘤。大多数病例发生在头颈部 64 例(52.9%)。
本研究得出的结论是,良性皮肤肿瘤的患病率略低于其他研究。大多数良性皮肤肿瘤为角化细胞肿瘤,其次是附属器肿瘤和黑素细胞肿瘤。软纤维瘤是最常见的良性角化细胞肿瘤。