Srinivas C V, Kailash N, Muniraju M, Savithri K L
Department of ENT, Dr. B. R. Ambedkar Medical College, K G Halli, Bangalore, 560045 India.
Indian J Otolaryngol Head Neck Surg. 2013 Jul;65(Suppl 1):167-70. doi: 10.1007/s12070-011-0341-4. Epub 2012 Mar 28.
Head and neck paragangliomas (HNPs) and pheochromocytomas are rare tumors. Catecholamine secreting tumors that arise from chromaffin cells of the adrenal medulla and the sympathetic ganglia are referred to as pheochromocytomas and extra adrenal catecholamine secreting paragangliomas (extra adrenal pheochromocytomas) respectively. The distinction between pheochromocytoma and paraganglioma is an important one because of implications for associated neoplasms, risk for malignancy, and genetic testing. Paragangliomas are rare tumors of the head and neck and are of diagnostic challenge. We report a case of 55 year old male who had a neck swelling, cough with expectoration, which on extensive evaluation revealed to be Paraganglioma with primary optic atrophy.
头颈部副神经节瘤(HNPs)和嗜铬细胞瘤是罕见肿瘤。起源于肾上腺髓质嗜铬细胞和交感神经节的儿茶酚胺分泌肿瘤分别称为嗜铬细胞瘤和肾上腺外儿茶酚胺分泌副神经节瘤(肾上腺外嗜铬细胞瘤)。嗜铬细胞瘤和副神经节瘤之间的区分很重要,因为这关系到相关肿瘤、恶性风险和基因检测。副神经节瘤是头颈部的罕见肿瘤,诊断具有挑战性。我们报告一例55岁男性病例,该患者有颈部肿胀、咳痰咳嗽症状,经过全面评估发现是伴有原发性视神经萎缩的副神经节瘤。