Sherwani Poonam, Anand Rama, Narula Mahender Kaur, Siddiqui Azaz Akhtar, Aggarwal Shilpi
Department of Radiodiagnosis, Lady Hardinge Medical College and Associated Hospitals, New Delhi, India.
Department of Surgery, Lady Hardinge Medical College and Associated Hospitals, New Delhi, India.
Indian J Radiol Imaging. 2015 Apr-Jun;25(2):198-201. doi: 10.4103/0971-3026.155879.
Paragangliomas are the neuroendocrine tumors which arise from the chromaffin cell. Tumors arising from the adrenal medulla are known as pheochromocytomas, while others originating from the extra-adrenal site are known as extra-adrenal paragangliomas. Paraganglioma can be multifocal which can arise synchronously or metachronously. Paragangliomas are less functionally active than the pheochromocytomas; they secrete noradrenaline and rarely dopamine, while adrenal pheochromocytomas secrete adrenaline or nor-adrenaline. Nonfunctional multifocal paragangliomas are very rare. We report a case of a 45-year-old female with multifocal nonfunctional paragangliomas of the retroperitoneum and urinarybladder which were surgically removed, and the diagnosis was confirmed on histopathology.
副神经节瘤是起源于嗜铬细胞的神经内分泌肿瘤。起源于肾上腺髓质的肿瘤称为嗜铬细胞瘤，而起源于肾上腺外部位的肿瘤称为肾上腺外副神经节瘤。副神经节瘤可以是多灶性的，可同时或异时发生。副神经节瘤的功能活性低于嗜铬细胞瘤；它们分泌去甲肾上腺素，很少分泌多巴胺，而肾上腺嗜铬细胞瘤分泌肾上腺素或去甲肾上腺素。无功能的多灶性副神经节瘤非常罕见。我们报告一例45岁女性，患有腹膜后和膀胱的多灶性无功能副神经节瘤，经手术切除，组织病理学确诊。
