Nakamura Junichi, Halliday Nicola Ann, Fukuba Eiji, Radjenovic Aleksandra, Tanner Steven F, Emery Paul, McGonagle Dennis, Tan Ai Lyn
From the UK National Institute for Health Research (NIHR) Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK; Department of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan; Department of Radiology, Faculty of Medicine, Shimane University, Shimane, Japan; Medical Physics and Engineering, Leeds Teaching Hospitals UK National Health Service (NHS) Trust, Leeds, UK.
J Rheumatol. 2014 Mar;41(3):523-7. doi: 10.3899/jrheum.130823. Epub 2014 Jan 15.
Hypervascularization in finger clubbing is recognized, but its microanatomical basis remains unclear. This pilot descriptive study used magnetic resonance imaging (MRI) to explore this further.
High-resolution MRI acquired with contrast agent was carried out in 4 patients with finger clubbing and 4 healthy volunteers. The anatomy of the nail bed, capsular structures, and bony changes were described.
Marked nail bed thickening and contrast enhancement was noted in all clubbed fingers, with bone edema in 3 of the 4 patients. None of the healthy subjects had similar abnormalities.
This confirms that hypervascularization of the nail bed observed in the microanatomy on high-resolution MRI is associated with clubbed appearances of the nails.
杵状指中的血管增生已得到认可，但其微观解剖学基础仍不清楚。这项初步描述性研究使用磁共振成像（MRI）对此进行进一步探索。
对4例杵状指患者和4名健康志愿者进行了使用造影剂的高分辨率MRI检查。描述了甲床、关节囊结构和骨质变化的解剖结构。
所有杵状指均观察到明显的甲床增厚和造影剂增强，4例患者中有3例出现骨水肿。健康受试者均无类似异常。
这证实了在高分辨率MRI微观解剖中观察到的甲床血管增生与杵状指外观有关。
