Department of Human Genetics, University of Michigan, Ann Arbor, Michigan, USA.
Theor Appl Genet. 1972 Jan;42(8):327-30. doi: 10.1007/BF00275356.
A general mathematical expression is found for the decrease in the fixation index of a population where subpopulations with different gene frequencies fuse. It is shown that the use of Wright's formulas for a hierarchic structure will not necessarily give the correct result in this situation, since the conditions for their application are usually not satisfied. Two examples are given, one with fusions among subpopulations with a continuously distributed gene frequency, and one with data from real observations producing a discrete distribution.
推导出了群体中具有不同基因频率的亚群融合时固定指数降低的一般数学表达式。结果表明，在这种情况下，使用 Wright 的层次结构公式不一定能得到正确的结果，因为通常不满足它们的应用条件。给出了两个例子，一个是亚群融合的例子，基因频率呈连续分布；另一个是根据真实观测数据得到离散分布的例子。
