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[胃肠道间质瘤手术治疗的诊断与策略]

[Diagnostics and tactics of gastrointestinal stromal tumor surgical treatment].

作者信息

Kriger A G, Starkov Iu G, Karmazanovskiĭ G G, Berelavichus S V, Gorin D S, Solodkiĭ A V, Vetsheva N N, Kurushkina N A

出版信息

Khirurgiia (Mosk). 2014(1):15-20.

PMID:24429709
Abstract

45 patients with gastrointestinal stromal tumors (GIST) were under observation. In 30 cases the GIST came from the stomach, in 8 cases - from the duodenum, and in 7 cases - from the small intestine. In all cases the diagnosis was confirmed by immunohistochemical study. Specific clinical manifestations of GIST were absent. Ultrasound detected the tumors that were more than 30 mm in diameter. The most informative diagnostic technique was computerized tomography with a contrast. All patients were operated. 29 patients with a diameter of tumor more than 50 mm had traditional open operation. In case the tumor oversteped the limits of the capsule or capsule's damage during the operation, the extirpation of the gastrocolic omentum was done. If the GIST were less than 50 mm they were extracted with the robot-assisted or laparoscopic methods. The long-term results of the treatment (from 3 to 60 months) of 28 patients were analyzed. 3 patients died of disease progression, 1 patient had metastasis in liver and 24 patients hadn't the signs of relapse.

摘要

对45例胃肠道间质瘤(GIST)患者进行了观察。其中30例GIST起源于胃,8例起源于十二指肠,7例起源于小肠。所有病例均经免疫组化研究确诊。GIST无特异性临床表现。超声检测到直径大于30mm的肿瘤。最具诊断价值的技术是增强计算机断层扫描。所有患者均接受了手术。29例肿瘤直径大于50mm的患者接受了传统开放手术。如果术中肿瘤超出包膜界限或包膜受损,则进行胃结肠网膜切除。如果GIST小于50mm,则采用机器人辅助或腹腔镜方法切除。分析了28例患者的长期治疗结果(3至60个月)。3例患者死于疾病进展,1例患者发生肝转移,24例患者无复发迹象。

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