小群体中的选择、连锁和显性：I. 对近交系数的影响。

Selection, linkage, and dominance in small populations : I. Effects on coefficient of inbreeding.

机构信息

Animal Health Research and Development, The Upjohn Company, 49001, Kalamazoo, Michigan, USA.

出版信息

Theor Appl Genet. 1971 Jan;41(3):130-5. doi: 10.1007/BF00277754.

Abstract

Linkage, dominance, and selection interact significantly to alter the mean coefficient of inbreeding. The effect of one is not predictable without the other two. Close linkage between adjacent loci in the presence of intense selection caused a different response with overdominant gene action from with partial dominance. When selection was random, effects of linkage and dominance on the coefficient of inbreeding were nonexistent; but when selection was by either phenotype or genotype, linkage and dominance became important. Joint effects between linkage, dominance, and selection are illustrated in specific simulated populations.

摘要

连锁、显性和选择相互作用显著改变了近交系数的均值。没有其他两个因素，一个因素的影响是不可预测的。在强烈选择的情况下，相邻基因座之间的紧密连锁导致了超显性基因作用与部分显性基因作用不同的反应。当选择是随机的时候，连锁和显性对近交系数的影响是不存在的；但是当选择是基于表型或基因型时，连锁和显性就变得很重要了。连锁、显性和选择之间的联合效应在特定的模拟群体中得到了说明。