以神经甾体生物合成作为创伤后应激障碍的治疗靶点。 - Suppr

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超能文献

Targeting neurosteroidogenesis as therapy for PTSD.

作者信息

Pinna Graziano

机构信息

Psychiatric Institute, Department of Psychiatry, University of Illinois at Chicago Chicago, IL, USA.

出版信息

Front Pharmacol. 2014 Jan 6;4:166. doi: 10.3389/fphar.2013.00166.

DOI:10.3389/fphar.2013.00166

PMID:24432002

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3880842/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ddb/3880842/61cf69abfb53/fphar-04-00166-g0001.jpg

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SSRIs and the female brain--potential for utilizing steroid-stimulating properties to treat menstrual cycle-linked dysphorias.SSRIs 和女性大脑——利用类固醇刺激特性治疗与月经周期相关的心境恶劣障碍的潜力。

J Psychopharmacol. 2013 Dec;27(12):1180-5. doi: 10.1177/0269881113490327. Epub 2013 May 23.

Prog Neuropsychopharmacol Biol Psychiatry. 2013 Aug 1;45:40-6. doi: 10.1016/j.pnpbp.2013.04.010. Epub 2013 Apr 23.

Up-regulation of neurosteroid biosynthesis as a pharmacological strategy to improve behavioural deficits in a putative mouse model of post-traumatic stress disorder.上调神经甾体生物合成作为一种改善创伤后应激障碍潜在小鼠模型行为缺陷的药理学策略。

J Neuroendocrinol. 2012 Jan;24(1):102-16. doi: 10.1111/j.1365-2826.2011.02234.x.

Evidence-based pharmacotherapy of post-traumatic stress disorder (PTSD).创伤后应激障碍（PTSD）的循证药物治疗。

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Neuroscience. 2011 Sep 15;191:55-77. doi: 10.1016/j.neuroscience.2011.03.025. Epub 2011 Mar 23.

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