1例少精子外瓶霉感染患者经伏立康唑治疗成功。
A case of Exophiala oligosperma successfully treated with voriconazole.
作者信息
Rimawi Bassam H, Rimawi Ramzy H, Mirdamadi Meena, Steed Lisa L, Marchell Richard, Sutton Deanna A, Thompson Elizabeth H, Wiederhold Nathan P, Lindner Jonathan R, Boger M Sean
机构信息
Medical University of South Carolina, Charleston, SC 29414, USA.
Brody School of Medicine - East Carolina University, Greenville, NC 27834, USA.
出版信息
Med Mycol Case Rep. 2013 Sep 8;2:144-7. doi: 10.1016/j.mmcr.2013.08.003.
Exophiala oligosperma is an uncommon pathogen associated with human infections, predominantly in immunocompromised hosts. Case reports of clinical infections related to E. oligosperma have been limited to 6 prior publications, all of which have shown limited susceptibility to conventional antifungal therapies, including amphotericin B, itraconazole, and fluconazole. We describe the first case of an E. oligosperma induced soft-tissue infection successfully treated with a 3-month course of voriconazole without persisting lesions.
少精子外瓶霉是一种与人类感染相关的罕见病原体，主要见于免疫功能低下的宿主。与少精子外瓶霉相关的临床感染病例报告此前仅限于6篇文献，所有这些报告均显示对包括两性霉素B、伊曲康唑和氟康唑在内的传统抗真菌疗法敏感性有限。我们描述了首例由少精子外瓶霉引起的软组织感染，通过3个月的伏立康唑疗程成功治愈且无持续病变。
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