Department of Mycology, Shanghai Dermatology Hospital, 1278 Baode Road, Shanghai, 200443, People's Republic of China.
Department of Mycology, Institute of Dermatology, Chinese Academy of Medical Science and Peking Union Medical College, Nanjing, People's Republic of China.
Mycopathologia. 2018 Oct;183(5):815-820. doi: 10.1007/s11046-018-0279-0. Epub 2018 Jun 26.
We report a case of subcutaneous infection caused by Exophiala oligosperma. Erythematous ulcerated plaque with exudate was major clinical features. Histopathological examination showed yeast-like cells and fungal hyphae. Mycological and molecular identification revealed E. oligosperma as etiologic agent. Local debridement and oral itraconazole were effective. To the best of our knowledge, this is the first report of phaeohyphomycosis caused by E. oligosperma in mainland China. This report highlights the potential role of E. oligosperma as an emerging cause of infection in immunocompetent patients.
我们报告了一例由寡孢外瓶霉引起的皮下感染。主要的临床特征是红斑溃疡性斑块伴渗出。组织病理学检查显示酵母样细胞和真菌菌丝。通过微生物学和分子鉴定，发现寡孢外瓶霉是病原体。局部清创和口服伊曲康唑有效。据我们所知，这是中国大陆首例由寡孢外瓶霉引起的暗色丝孢霉病报告。本报告强调了寡孢外瓶霉作为免疫功能正常患者感染的新兴病因的潜在作用。
