Department of Internal Medicine, Buffalo, NY.
J Clin Hypertens (Greenwich). 2014 Feb;16(2):127-32. doi: 10.1111/jch.12249. Epub 2014 Jan 17.
Cardiovascular disease (CVD) is the leading cause of death in renal transplant recipients (RTRs). Clinical inertia (CI) is defined as "recognition of the problem, but failure to act." The effect of educational interventions in minimizing CI in CVD risk factor management was assessed. Educational sessions were conducted among 201 RTRs to inform them about their goals for blood pressure (BP), low-density lipoprotein cholesterol (LDL-C) and glycated hemoglobin (HbA1c). Physicians were reminded about treatment goals using checklists. Pre-intervention and post-intervention CI was measured as "no action" or "appropriate action" by the physicians. Post-intervention percentage of RTRs with "no clinical action" for BP, LDL-C, and HbA1c control decreased from 10.8% to 3.8% (P=.02), 28.2% to 11.1% (P=.008), and 10.3% to 4.5% (P=.05), respectively, while those with "appropriate action" increased from 66.2% to 83.3% (P<.001), 68.7% to 79.4% (P=.008), and 85.1% to 93.2% (P=.03), respectively. Educational interventions and patient participation were shown to reduce CI.
心血管疾病(CVD)是肾移植受者(RTR)死亡的主要原因。临床惰性(CI)被定义为“认识到问题,但未能采取行动”。评估了教育干预在最小化 CVD 风险因素管理中的 CI 的效果。对 201 名 RTR 进行了教育课程,告知他们血压(BP)、低密度脂蛋白胆固醇(LDL-C)和糖化血红蛋白(HbA1c)的目标。使用清单提醒医生有关治疗目标。通过医生的“无行动”或“适当行动”来衡量干预前后的 CI。干预后,血压、LDL-C 和 HbA1c 控制的无临床行动的 RTR 百分比从 10.8%降至 3.8%(P=.02)、28.2%降至 11.1%(P=.008)和 10.3%降至 4.5%(P=.05),而适当行动的百分比从 66.2%增加到 83.3%(P<.001)、68.7%增加到 79.4%(P=.008)和 85.1%增加到 93.2%(P=.03)。教育干预和患者参与被证明可以减少 CI。