Sun Xu-guang, Zhou Yu-mei, Jiang Chao, Wang Zhi-qun, Zhang Yang
Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology & Visual Sciences Key Lab, Beijing 100038, China. Email:
Zhonghua Yan Ke Za Zhi. 2013 Oct;49(10):878-83.
To summarize the clinical characteristics and the therapy effect of blepharitis patients in clinic.
Retrospective case series study.Four hundred and thirty-eight patients were diagnosed clinically as blepharitis in Beijing Tongren Hospital from Jan 2009 to July 2012. Analyzed the general states of health, case history, and the clinical manifestation, to summarize the clinical characteristics of blepharitis. The patients were clinically degree indexing and treated appropriately. After 1-2 courses of the treatment, the effect was analyzed.main outcome measures:manifestation of lid margin, corneal, conjunctiva, and the results of tear tests.
Four hundred and thirty-eight patients were recorded, from 3 to 84 years old, and the average was 40 ± 18 years old.435 (99.3%) cases were suffered with double eyes.159(26.3%) cases were males, and 279 (63.7%) cases were females. Children group had 41 cases (9.4%), which from 0 to 16 years old. Adult group (17-59 years) included 331 cases, which were 75.6% in the study. 66 cases were in aged group ( ≥ 60 years), being 15.0% in all cases.176 cases (40.2%) were on mild stage, 174 cases (39.7%) on middle stage, and 88 cases (20.1%) were on serious stage. Aged group were significantly more than children group (χ(2) = 34.575, P < 0.05).No significant difference between male and female (χ(2) = 32.877, P = 0.192). In 222 cases (50.7%) blepharitis patients complicated with correlation of keratoconjunctivitis lesions, respectively 8.5%, 75.3% and 86.4% in the mild, moderate, and severe patients. Adult group cases were significantly more than Children and aged group (χ(2) = 362.785, P < 0.05). Aged group were significantly more than Children group (χ(2) = 362.785, P < 0.05). 303 cases (69.2%)were with tear abnormal. The moderate and serious patients were more suffered with tear abnormal than mild patients (χ(2) = 64.438, P = 0.000). Patients were followed up for 1.5 to 27 months, mean 8 months. According to different extent of blepharitis, patients were given 1 courses of treatment.333 cases were clinical recovery, and the other cases were improved obviously.
Blepharitis occurs mainly in adults.It always complicate with dry eye and keratoconjunctival lesions.It is needed pay attention to by Ophthalmologist. The diagnosis and grade is based on typical clinical symptoms. The treatment according different grades should focus on the correct handling of the palpebral margin.
总结临床睑缘炎患者的临床特征及治疗效果。
回顾性病例系列研究。2009年1月至2012年7月在北京同仁医院临床诊断为睑缘炎的患者438例。分析其健康总体状况、病史及临床表现，总结睑缘炎的临床特征。对患者进行临床分度并给予相应治疗。治疗1 - 2个疗程后分析疗效。主要观察指标：睑缘、角膜、结膜表现及泪液检查结果。
共记录438例患者，年龄3至84岁，平均年龄40±18岁。435例（99.3%）为双眼患病。男性159例（26.3%），女性279例（63.7%）。儿童组41例（9.4%），年龄0至16岁。成人组（17 - 59岁）331例，占研究病例的75.6%。老年组（≥60岁）66例，占所有病例的15.0%。轻度176例（40.2%），中度174例（39.7%），重度88例（20.1%）。老年组显著多于儿童组（χ(2)=34.575，P<0.05）。男女之间无显著差异（χ(2)=32.877，P = 0.192）。222例（50.7%）睑缘炎患者合并角膜结膜炎相关病变，轻度、中度和重度患者分别为8.5%、75.3%和86.4%。成人组病例显著多于儿童组和老年组（χ(2)=362.785，P<0.05）。老年组显著多于儿童组（χ(2)=362.785，P<0.05）。303例（69.2%）有泪液异常。中度和重度患者泪液异常比轻度患者更常见（χ(2)=64.438，P = 0.ooo）。患者随访1.5至27个月，平均8个月。根据睑缘炎不同程度给予1个疗程治疗。333例临床痊愈，其余病例明显改善。
睑缘炎主要发生于成人。常合并干眼及角膜结膜病变。眼科医生应予以关注。诊断及分级依据典型临床症状。针对不同分级的治疗应注重睑缘的正确处理。
