Chuang E L
Retinal Diagnostic Department, Moorfields Eye Hospital, London.
Eye (Lond). 1987;1 ( Pt 2):311-7. doi: 10.1038/eye.1987.50.
Age-related Macular Degeneration (AMD) is responsible for the majority of registered blindness in the elderly. Laser photocoagulation can be offered as a treatment of proven value to only a proportion of patients with neovascular AMD. Clinically, our expectations must be tempered by the high incidence of recurrent subretinal vessels, the anatomic limitations of treatable lesions and the large number of ageing eyes for which there is no place for laser. In addition to improvements in education, referral habits and the application of laser therapy which may have an impact upon visual loss due to AMD, there are promising directions to be explored in alternative modes of treatment and prevention.
年龄相关性黄斑变性(AMD)是导致老年人登记失明的主要原因。激光光凝仅对一部分新生血管性AMD患者具有经证实的治疗价值。在临床上,由于视网膜下血管复发的高发生率、可治疗病变的解剖学限制以及大量不适用于激光治疗的老龄眼睛,我们的期望必须有所调整。除了在教育、转诊习惯以及激光治疗应用方面的改进可能会对AMD导致的视力丧失产生影响外,在替代治疗和预防模式方面还有一些有前景的方向有待探索。