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西班牙择期结肠癌手术中快速康复方案依从性的观察性横断面研究。

Observational cross-sectional study of compliance with the fast track protocol in elective surgery for colon cancer in Spain.

作者信息

Alcántara-Moral Manuel, Serra-Aracil X, Gil-Egea M J, Frasson M, Flor-Lorente B, Garcia-Granero E

机构信息

General and Digestive Surgery Service, Hospital Universitario Parc Tauli, Parc Tauli s/n, 08208, Sabadell, Barcelona, Spain,

出版信息

Int J Colorectal Dis. 2014 Apr;29(4):477-83. doi: 10.1007/s00384-013-1825-3. Epub 2014 Jan 17.

Abstract

PURPOSE

The purpose of this study was to establish the degree of compliance with the fast track (enhanced recovery) protocol in habitual clinical practice and to determine which measures are fundamental for achieving the results obtained by applying the entire protocol.

METHODS

Observational, cross-sectional, multicenter trial was conducted. Participating hospitals prospectively recorded data from at least ten consecutive patients undergoing surgery for colon cancer who were applied some or all of the items comprising the enhanced recovery protocol. The data were analyzed both globally and dividing the sample into the two groups of patients.

RESULTS

Data on 363 patients from 25 hospitals were recorded, one hundred seventy-three in the "non-fast track" group and 190 in the "fast track" group. The non-fast track group complied with a mean of 5.4 (±1.8) items and the fast track group with a mean of 8.4 (±1.8) items. The mean functional hospital stay was 7.3 (±5.1) days in the non-fast track group and 6.2 (±5.1) days in the fast track group (p < 0.05). Morbidity was 31.1 % in the fast track group and 24.3 % in the non-fast track group, though the differences were not statistically significant. The only prognostic factors that have an impact on improving the results are measures against hypothermia and mobilization before 24 h.

CONCLUSION

Compliance with the enhanced recovery protocol is not exhaustive in habitual clinical practice. However, greater compliance was associated with shorter hospital stay without any increase in morbidity. The only items clearly associated with reduced functional hospital stay were measures against hypothermia and mobilization before 24 h.

摘要

目的

本研究的目的是确定在常规临床实践中对快速康复(强化康复)方案的依从程度,并确定哪些措施对于通过应用整个方案所取得的结果至关重要。

方法

进行了一项观察性、横断面、多中心试验。参与研究的医院前瞻性地记录了至少连续10例接受结肠癌手术患者的数据,这些患者接受了强化康复方案中的部分或全部项目。对数据进行了整体分析,并将样本分为两组患者进行分析。

结果

记录了来自25家医院的363例患者的数据,“非快速康复”组173例,“快速康复”组190例。非快速康复组平均依从5.4(±1.8)项,快速康复组平均依从8.4(±1.8)项。非快速康复组的平均住院功能天数为7.3(±5.1)天,快速康复组为6.2(±5.1)天(p<0.05)。快速康复组的发病率为31.1%,非快速康复组为24.3%,尽管差异无统计学意义。对改善结果有影响的唯一预后因素是预防体温过低的措施和24小时前的活动。

结论

在常规临床实践中,对强化康复方案的依从性并不完全。然而,更高的依从性与缩短住院时间相关,且发病率没有增加。与缩短住院功能天数明显相关的唯一项目是预防体温过低的措施和24小时前的活动。

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