Division of General and Thoracic Surgery, The Hospital for Sick Children, Toronto, ON, Canada.
Division of General and Thoracic Surgery, The Hospital for Sick Children, Toronto, ON, Canada.
J Pediatr Surg. 2014 Jan;49(1):87-90; discussion 90. doi: 10.1016/j.jpedsurg.2013.09.032. Epub 2013 Oct 8.
The purpose of this study was to compare the clinical outcomes of loop and divided colostomies in patients with anorectal malformations (ARM).
We performed a retrospective cohort study reviewing the medical records of all patients with ARM managed with diverting colostomies between 2000 and 2010 at our institution. Independent variables and outcomes of stoma complications were analyzed by parametric measures and logistic regression.
One hundred forty-four patients managed with a colostomy for ARM were evaluated (37.5% females, 50.7% loop, 49.3% divided). The incidence of patients with loop and divided colostomies who developed stoma-related complications was 31.5 and 15.5%, respectively (p=0.031). The incidence of prolapse was 17.8 and 2.8%, respectively (p=0.005). Multivariable-logistic regression controlling for other significant independent variables found loop colostomies to be positively associated with the development of a stoma complication (OR 3.13, 95%CI (1.09, 8.96), p=0.033). When individual complications were evaluated, it was only stoma prolapse that was more likely in patients with loop colostomies (OR 8.75, 95%CI (1.74, 44.16), p=0.009).
Because of the higher incidence of prolapse, loop colostomies were found to be associated with a higher total incidence of complications than divided stomas. The development of other complications, including urinary tract infections (UTIs) and megarectum, were independent of the type of colostomy performed.
本研究旨在比较直肠肛门畸形(ARM)患者中环形和分割式结肠造口术的临床结果。
我们对 2000 年至 2010 年间在本机构接受造口术治疗的所有 ARM 患者的病历进行了回顾性队列研究。通过参数测量和逻辑回归分析独立变量和造口并发症的结果。
评估了 144 例接受 ARM 结肠造口术治疗的患者(女性占 37.5%,环形造口占 50.7%,分割式造口占 49.3%)。发生与造口相关并发症的环形和分割式造口患者的发生率分别为 31.5%和 15.5%(p=0.031)。脱垂的发生率分别为 17.8%和 2.8%(p=0.005)。多变量逻辑回归控制其他显著的独立变量后发现,环形造口术与造口并发症的发生呈正相关(OR 3.13,95%CI(1.09,8.96),p=0.033)。当评估单个并发症时,只有环形造口术更容易发生造口脱垂(OR 8.75,95%CI(1.74,44.16),p=0.009)。
由于脱垂的发生率较高,与分割式造口术相比,环形造口术与更高的总并发症发生率相关。包括尿路感染(UTIs)和巨直肠在内的其他并发症的发生与所进行的造口术类型无关。