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本文引用的文献

1
Oxidative Stress.氧化应激
EcoSal Plus. 2009 Aug;3(2). doi: 10.1128/ecosalplus.5.4.4.
2
Disparate impact of oxidative host defenses determines the fate of Salmonella during systemic infection in mice.氧化应激宿主防御的差异决定了鼠全身性感染沙门氏菌的命运。
Cell Host Microbe. 2014 Jan 15;15(1):72-83. doi: 10.1016/j.chom.2013.12.006.
3
Dynamics of spread of Salmonella enterica in the systemic compartment.鼠伤寒沙门氏菌在全身系统中的传播动力学。
Microbes Infect. 2013 Nov;15(13):849-57. doi: 10.1016/j.micinf.2013.10.003. Epub 2013 Oct 30.
4
Functions of the Salmonella pathogenicity island 2 (SPI-2) type III secretion system effectors.沙门氏菌致病性岛 2（SPI-2）型 III 型分泌系统效应物的功能。
Microbiology (Reading). 2012 May;158(Pt 5):1147-1161. doi: 10.1099/mic.0.058115-0. Epub 2012 Mar 15.
5
How does the oxidative burst of macrophages kill bacteria? Still an open question.巨噬细胞的氧化爆发如何杀死细菌？仍是一个悬而未决的问题。
Mol Microbiol. 2011 May;80(3):580-3. doi: 10.1111/j.1365-2958.2011.07612.x. Epub 2011 Mar 14.
6
Phagocytic superoxide specifically damages an extracytoplasmic target to inhibit or kill Salmonella.吞噬细胞超氧化物特异性地损伤胞外靶点以抑制或杀死沙门氏菌。
PLoS One. 2009;4(3):e4975. doi: 10.1371/journal.pone.0004975. Epub 2009 Mar 23.
7
Hemophagocytic macrophages harbor Salmonella enterica during persistent infection.在持续性感染期间，噬血细胞性巨噬细胞会藏匿肠道沙门氏菌。
PLoS Pathog. 2007 Dec;3(12):e193. doi: 10.1371/journal.ppat.0030193.
8
Modeling the reactions of superoxide and myeloperoxidase in the neutrophil phagosome: implications for microbial killing.模拟中性粒细胞吞噬小体中超氧化物和髓过氧化物酶的反应：对微生物杀伤的影响。
J Biol Chem. 2006 Dec 29;281(52):39860-9. doi: 10.1074/jbc.M605898200. Epub 2006 Oct 30.
9
Antimicrobial reactive oxygen and nitrogen species: concepts and controversies.抗菌活性氧和氮物种：概念与争议
Nat Rev Microbiol. 2004 Oct;2(10):820-32. doi: 10.1038/nrmicro1004.
10
Antimicrobial actions of the NADPH phagocyte oxidase and inducible nitric oxide synthase in experimental salmonellosis. II. Effects on microbial proliferation and host survival in vivo.NADPH 吞噬细胞氧化酶和诱导型一氧化氮合酶在实验性沙门氏菌病中的抗菌作用。II. 对体内微生物增殖和宿主存活的影响。
J Exp Med. 2000 Jul 17;192(2):237-48. doi: 10.1084/jem.192.2.237.

沙门氏菌杀伤中的吞噬细胞轮盘赌。

Phagocyte roulette in Salmonella killing.

机构信息

Department of Microbiology, University of Illinois, Urbana, IL 61801-3709, USA.

Department of Microbiology, University of Illinois, Urbana, IL 61801-3709, USA; College of Medicine, University of Illinois, Urbana, IL 61801-3709, USA.

出版信息

Cell Host Microbe. 2014 Jan 15;15(1):7-8. doi: 10.1016/j.chom.2014.01.001.

DOI:10.1016/j.chom.2014.01.001
PMID:24439894
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3936476/
Abstract

Salmonella propagates in macrophages to cause life-threatening infections, but the role of neutrophils in combating Salmonella has been controversial. In this issue, Burton et al. (2014) use single cell analyses and modeling to explain the ability of Salmonella to survive in macrophages while being killed by neutrophils.

摘要

沙门氏菌在巨噬细胞中繁殖会导致危及生命的感染，但中性粒细胞在对抗沙门氏菌方面的作用一直存在争议。在本期杂志中，Burton 等人（2014 年）使用单细胞分析和建模来解释沙门氏菌在被中性粒细胞杀死的同时在巨噬细胞中存活的能力。