Section of Microbiology, Universitetsparken 15, Department of Biology, Faculty of Science, University of Copenhagen, 2100 Copenhagen Ø, Denmark.
Section of Microbiology, Universitetsparken 15, Department of Biology, Faculty of Science, University of Copenhagen, 2100 Copenhagen Ø, Denmark.
Trends Microbiol. 2014 Feb;22(2):84-91. doi: 10.1016/j.tim.2013.12.004. Epub 2014 Jan 15.
The recent focus on complex bacterial communities has led to the recognition of interactions across species boundaries. This is particularly pronounced in multispecies biofilms, where synergistic interactions impact the bacterial distribution and overall biomass produced. Importantly, in a number of settings, the interactions in a multispecies biofilm affect its overall function, physiology, or surroundings, by resulting in enhanced resistance, virulence, or degradation of pollutants, which is of significant importance to human health and activities. The underlying mechanisms causing these synergistic effects are to some extent characterized at the molecular and evolutionary levels, and further exploration is now possible due to the enhanced resolution and higher throughput of available techniques.
近期对复杂细菌群落的关注导致了人们对跨越物种界限的相互作用的认识。这在多物种生物膜中尤为明显，协同作用会影响细菌的分布和产生的总体生物量。重要的是，在许多情况下，多物种生物膜中的相互作用会通过增强抗药性、毒性或污染物的降解来影响其整体功能、生理机能或周围环境，这对人类健康和活动具有重要意义。这些协同效应的潜在机制在一定程度上已在分子和进化水平上得到了描述，并且由于现有技术的分辨率提高和通量增加，现在可以进一步进行探索。
