Department of Internal Medicine, Cardinal Tien Hospital, School of Medicine, Fu-Jen Catholic University, New Taipei City, Taiwan.
Department of Medical Research, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Chiayi, Taiwan.
Int J Cardiol. 2014 Mar 1;172(1):82-7. doi: 10.1016/j.ijcard.2013.12.082. Epub 2014 Jan 7.
This nationwide population-based study investigated the relationship between individual and neighborhood socioeconomic status (SES) and mortality rates for acute myocardial infarction (AMI) in Taiwan.
A population-based follow-up study included 23,568 patients diagnosed with AMI from 2004 to 2008. Each patient was monitored for 2 years, or until their death, whichever came first. The individual income-related insurance payment amount was used as a proxy measure of patient's individual SES. Neighborhood SES was defined by household income, and neighborhoods were grouped as advantaged or disadvantaged. The Cox proportional hazards model was used to compare the mortality rates between the different SES groups after adjusting for possible confounding risk factors.
After adjusting for potential confounding factors, AMI patients with low individual SES had an increased risk of death than those with high individual SES who resided in advantaged neighborhoods. In contrast, the cumulative readmission rate from major adverse cardiovascular events did not differ significantly between the different individual and neighborhood SES groups. AMI patients with low individual SES had a lower rate of diagnostic angiography and subsequent percutaneous coronary intervention (P<0.001). The presence of congestive heart failure, chronic kidney disease, chronic obstructive pulmonary disease, pneumonia, septicemia, and shock revealed an incremental increase with worse SES (P<0.001).
The findings indicate that AMI patients with low individual SES have the greatest risk of short-term mortality despite being under a universal health-care system. Public health strategies and welfare policies must continue to focus on this vulnerable group.
本全国性基于人群的研究调查了个体和邻里社会经济地位(SES)与台湾急性心肌梗死(AMI)死亡率之间的关系。
一项基于人群的随访研究纳入了 2004 年至 2008 年期间被诊断为 AMI 的 23568 例患者。每个患者都被监测了 2 年,或直至死亡,以先发生者为准。个体收入相关的保险支付金额被用作患者个体 SES 的替代指标。邻里 SES 由家庭收入定义,并将邻里分为优势和劣势两类。Cox 比例风险模型用于比较调整潜在混杂风险因素后不同 SES 组之间的死亡率。
在调整了潜在混杂因素后,社会经济地位较低的 AMI 患者死亡风险高于社会经济地位较高且居住在优势邻里的患者。相比之下,不同个体和邻里 SES 组之间的主要不良心血管事件的再入院率无显著差异。社会经济地位较低的 AMI 患者接受诊断性血管造影和随后的经皮冠状动脉介入治疗的比例较低(P<0.001)。充血性心力衰竭、慢性肾脏病、慢性阻塞性肺疾病、肺炎、败血症和休克的存在随着 SES 恶化而呈递增趋势(P<0.001)。
尽管有全民医疗保健系统,社会经济地位较低的 AMI 患者仍具有最大的短期死亡风险。公共卫生策略和福利政策必须继续关注这一弱势群体。