Araujo Júnior E, Martins Wellington P, Pares David Baptista Silva, Pires Claudio Rodrigues, Filho Sebastião Marques Zanforlin
J Perinat Med. 2014 Jul;42(4):535-9. doi: 10.1515/jpm-2013-0293.
The aim of this study was to determine the reference range for amniotic fluid index (AFI) measurements in a large sample of the Brazilian population.
This was a retrospective cross-sectional study on 3837 normal singleton pregnancies between 18+0 and 38+6 weeks of pregnancy. The AFI was measured from the largest vertical pockets of amniotic fluid in the four quadrants of the uterine cavity. To assess the correlation between AFI and gestational age (GA), polynomial equations were calculated, with adjustments using the determination coefficient (R2).
The mean maternal age and gestational age were 27.01±6.57 years and 30.43±5.29 weeks, respectively. The mean AFI ranged from 12.2±2.6 cm at 18 weeks to 11.6±6.0 cm at 38 weeks of pregnancy. The correlation between AFI and GA was best represented by a linear equation: AFI=17.78-0.153*GA (R2=0.027).
We established the reference range for the AFI in a large sample of the Brazilian population. This reference range can be used to monitor deviations in the volume of amniotic fluid in fetuses at high risk for intrauterine growth disturbances.
本研究旨在确定巴西人群大样本中羊水指数（AFI）测量的参考范围。
这是一项对3837例孕18⁺⁰至38⁺⁶周的正常单胎妊娠进行的回顾性横断面研究。AFI通过测量子宫腔四个象限中羊水最大垂直深度来确定。为评估AFI与孕周（GA）之间的相关性，计算多项式方程，并使用决定系数（R²）进行调整。
产妇平均年龄和孕周分别为27.01±6.57岁和30.43±5.29周。平均AFI范围从孕18周时的12.2±2.6 cm到孕38周时的11.6±6.0 cm。AFI与GA之间的相关性最好用线性方程表示：AFI = 17.78 - 0.153×GA（R² = 0.027）。
我们在巴西人群大样本中建立了AFI的参考范围。该参考范围可用于监测有宫内生长发育障碍高风险胎儿的羊水量偏差。
