Iball Gareth R, Tout Deborah
aDepartment of Medical Physics and Engineering, Leeds Teaching Hospital NHS Trust, Leeds bCentral Manchester University Hospitals NHS Foundation Trust, Manchester, UK.
Nucl Med Commun. 2014 Apr;35(4):372-81. doi: 10.1097/MNM.0000000000000064.
Computed tomography (CT) automatic exposure control (AEC) systems are now used in all modern PET-CT scanners. A collaborative study was undertaken to compare AEC techniques of the three major PET-CT manufacturers for fluorine-18 fluorodeoxyglucose half-body oncology imaging.
An audit of 70 patients was performed for half-body CT scans taken on a GE Discovery 690, Philips Gemini TF and Siemens Biograph mCT (all 64-slice CT). Patient demographic and dose information was recorded and image noise was calculated as the SD of Hounsfield units in the liver. A direct comparison of the AEC systems was made by scanning a Rando phantom on all three systems for a range of AEC settings.
The variation in dose and image quality with patient weight was significantly different for all three systems, with the GE system showing the largest variation in dose with weight and Philips the least. Image noise varied with patient weight in Philips and Siemens systems but was constant for all weights in GE. The z-axis mA profiles from the Rando phantom demonstrate that these differences are caused by the nature of the tube current modulation techniques applied. The mA profiles varied considerably according to the AEC settings used.
CT AEC techniques from the three manufacturers yield significantly different tube current modulation patterns and hence deliver different doses and levels of image quality across a range of patient weights. Users should be aware of how their system works and of steps that could be taken to optimize imaging protocols.
计算机断层扫描(CT)自动曝光控制(AEC)系统现用于所有现代PET-CT扫描仪。开展了一项合作研究,比较三大PET-CT制造商用于氟-18氟脱氧葡萄糖半身肿瘤成像的AEC技术。
对70例患者进行了半身CT扫描审核,扫描设备为GE Discovery 690、飞利浦Gemini TF和西门子Biograph mCT(均为64层CT)。记录患者人口统计学和剂量信息,并将图像噪声计算为肝脏中亨氏单位的标准差。通过在所有三个系统上对Rando体模进行一系列AEC设置扫描,对AEC系统进行直接比较。
所有三个系统的剂量和图像质量随患者体重的变化存在显著差异,GE系统的剂量随体重变化最大,飞利浦系统最小。飞利浦和西门子系统的图像噪声随患者体重变化,但GE系统中所有体重的图像噪声均保持恒定。来自Rando体模的z轴毫安分布图表明,这些差异是由所应用的管电流调制技术的性质引起的。毫安分布图根据所使用的AEC设置有很大差异。
三大制造商的CT AEC技术产生显著不同的管电流调制模式,因此在一系列患者体重范围内提供不同的剂量和图像质量水平。用户应了解其系统的工作方式以及可采取哪些步骤来优化成像方案。