Miwa Masanao, You Gyokukou, Tanaka Hideaki, Taniguchi Seigo, Fujii Takahiro, Kamemura Kazuo, Suzaki Masafumi, Isono Takahiro, Tooyama Ikuo, Tanaka Masakazu, Srivatanakul Petcharin, Viwatthanasittiphong Chutiwan, Sangrajrang Suleeporn, Khuhaprema Thiravud
Nagahama Institute of Bio-Science and Technology, 1266 Tamura-cho, Nagahama, Shiga, 526-0829, Japan.
J Hepatobiliary Pancreat Sci. 2014 Jun;21(6):397-8. doi: 10.1002/jhbp.69. Epub 2014 Jan 21.
Cholangiocarcinoma is one of the most serious diseases in northeast Thailand, where its incidence is reported to be the highest in the world. We tried to develop a new method to detect cholangiocarcinoma in the early stages using serum proteins. We found that after fluorescent labeling of the sugar moiety of serum proteins, a new peak was identified, which might be a promising marker for cholangiocarcinoma.
胆管癌是泰国东北部最严重的疾病之一,据报道该地区胆管癌发病率为全球最高。我们试图开发一种利用血清蛋白在早期检测胆管癌的新方法。我们发现,在对血清蛋白的糖部分进行荧光标记后,识别出了一个新峰,它可能是胆管癌的一个有前景的标志物。