Cetin Mustafa, Ozturk Unal, Cakici Musa, Yildiz Emrah
Department of Cardiology, Adiyaman University, Adiyaman, Turkey.
BMJ Case Rep. 2014 Jan 21;2014:bcr2013201189. doi: 10.1136/bcr-2013-201189.
Behcet's disease (BD) is a multisystemic inflammatory disorder of unknown origin, presenting with mucocutaneous, ocular, articular, vascular, gastrointestinal and central nervous system manifestations. Coronary involvement is very rare in patients with BD. Sildenafil, an oral drug used to treat erectile dysfunction, was shown to cause significant cardiovascular problems including acute myocardial infarction (MI) and sudden cardiac death. Acute MI associated with BD and sildenafil has not been reported previously. We present a case of a 23-year-old male patient with an acute inferior MI associated with BD diagnosed after admission of sildenafil, who was successfully treated with thrombus aspiration and tirofiban administration.
白塞病（BD）是一种病因不明的多系统炎症性疾病，表现为皮肤黏膜、眼部、关节、血管、胃肠道及中枢神经系统症状。白塞病患者冠状动脉受累极为罕见。西地那非是一种用于治疗勃起功能障碍的口服药物，已证实会引发严重心血管问题，包括急性心肌梗死（MI）和心源性猝死。此前尚无白塞病与西地那非相关的急性心肌梗死报道。我们报告一例23岁男性患者，在服用西地那非后入院诊断为与白塞病相关的急性下壁心肌梗死，经血栓抽吸和替罗非班治疗后成功治愈。
