Rosenbach F, Richter M, Pförtner T-K
Institut für Medizinische Soziologie , Martin-Luther-Universität Halle-Wittenberg, Magdeburger Str. 8, 06112, Halle (Saale), Deutschland,
Herz. 2015 May;40 Suppl 3:298-304. doi: 10.1007/s00059-013-4040-7. Epub 2014 Jan 23.
In light of the consistent SES gradient in cardiovascular diseases, current research is focusing on possible pathways through which the socioeconomic status (SES) may impact health. Inflammatory processes play a critical role in the development of cardiovascular diseases and are associated with stress. Therefore, they might be one psychobiological pathway explaining how the SES gets under the skin. Considering the different meanings of education, occupation and income, this article gives an overview of the association between inflammatory biomarkers and socioeconomic status.
There is high evidence for associations between indicators of SES - education, occupation and income - and inflammatory biomarkers. Possible pathways are health status, health behavior and psychobiological processes as a result of increased exposure to psychosocial stress.
The SES gradient in cardiovascular diseases reflects behavioral as well as physiological pathways and systemic inflammation seems to be involved. Low SES is associated with an increased exposure to adverse circumstances of life, which can trigger biological responses and result in an increased risk of cardiovascular diseases. Medical history taking in cardiology should focus on socio-structural exposures and thereby reflect the different meanings of education, occupation and income.
鉴于心血管疾病中社会经济地位(SES)梯度的一致性,当前研究聚焦于社会经济地位可能影响健康的潜在途径。炎症过程在心血管疾病的发展中起关键作用,且与压力相关。因此,它们可能是解释社会经济地位如何影响健康的一种心理生物学途径。考虑到教育、职业和收入的不同含义,本文概述了炎症生物标志物与社会经济地位之间的关联。
有充分证据表明社会经济地位指标——教育、职业和收入——与炎症生物标志物之间存在关联。可能的途径包括健康状况、健康行为以及因心理社会压力增加而产生的心理生物学过程。
心血管疾病中的社会经济地位梯度反映了行为和生理途径,且系统性炎症似乎也与之相关。低社会经济地位与更多接触不良生活环境有关,这可能引发生物学反应并导致心血管疾病风险增加。心脏病学中的病史采集应关注社会结构暴露情况,从而反映教育、职业和收入的不同含义。