Rheumatology and Clinical Immunology, Department of Clinical and Experimental Sciences, Spedali Civili and University of Brescia, Brescia, Italy,
Curr Rheumatol Rep. 2014 Mar;16(3):405. doi: 10.1007/s11926-013-0405-4.
One of the challenges of managing patients with antiphospholipid syndrome is the prevention of rethrombosis (secondary prophylaxis). Risk stratification, i.e. traditional cardiovascular and thrombosis risk factors, systemic autoimmune diseases, antiphospholipid antibody profile, and the intensity of anticoagulation are all relevant to the management of APS patients with recurrent thrombosis. The paper will review "state of the art" strategies for optimizing therapy for APS patients with recurrent thrombosis.
管理抗磷脂综合征患者的挑战之一是预防再血栓形成(二级预防)。风险分层,即传统的心血管和血栓形成危险因素、系统性自身免疫性疾病、抗磷脂抗体谱和抗凝强度,都与复发性血栓形成的 APS 患者的管理相关。本文将回顾优化复发性血栓形成的 APS 患者治疗的“最新”策略。