Cray Carolyn, Hammond Elizabeth, Haefele Holly
Division of Comparative Pathology, University of Miami Miller School of Medicine, P.O. Box 016960 (R-46), Miami, FL 33101, USA.
Lion Country Safari, 2003 Lion Country Safari Road, Loxahatchee, FL 33470, USA.
J Zoo Wildl Med. 2013 Dec;44(4):1107-10. doi: 10.1638/2013-0033R.1.
Grant's zebra (Equus burchelli) are commonly kept in zoos and are subject to routine health monitoring and research studies. Recently, assays for acute phase proteins (APP) have been described in many wildlife species, and specific assays for serum amyloid A (SAA) have been well validated and studied in horses (Equus ferus caballus), in which it serves as a major APP. In the present study, serum samples from 26 Grant's zebra were subject to analysis by using assays for SAA, haptoglobin (HP), and protein electrophoresis. Reference intervals were calculated by using the robust method: SAA 1.8-31.4 mg/L and HP 0.37-1.58 mg/ml. Significant differences in SAA and HP were observed in clinically abnormal zebra; in some cases, these differences were marked and were noted in the absence of abnormal values for protein electrophoretic fractions. These data indicate that APP may be a valuable and sensitive tool in monitoring inflammation in this species.
格兰特斑马（Equus burchelli）通常饲养在动物园中，并接受常规健康监测和研究。最近，许多野生动物物种都描述了急性期蛋白（APP）的检测方法，并且血清淀粉样蛋白A（SAA）的特定检测方法在马（Equus ferus caballus）中已经得到了很好的验证和研究，在马中它是主要的APP。在本研究中，对26只格兰特斑马的血清样本进行了SAA、触珠蛋白（HP）检测和蛋白电泳分析。采用稳健方法计算参考区间：SAA为1.8 - 31.4 mg/L，HP为0.37 - 1.58 mg/ml。在临床异常的斑马中观察到SAA和HP有显著差异；在某些情况下，这些差异很明显，并且在蛋白电泳组分无异常值的情况下也被注意到。这些数据表明，APP可能是监测该物种炎症的一种有价值且敏感的工具。
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