Homann G, Fahrendorf D, Niederstadt T, Nagelmann N, Heindel W, Lütkenhöner B, Böckenfeld Y, Basel T, Vieth V
Department of Clinical Radiology, University Hospital Münster.
ENT Clinic, University Hospital Münster.
Rofo. 2014 Mar;186(3):225-9. doi: 10.1055/s-0033-1356221. Epub 2014 Jan 22.
The synchronous appearance of different inner ear pathologies with a nearly equivalent clinical manifestation such as Menière's disease and vestibular schwannoma is very rare but leads to a relevant dilemma concerning therapy options. MRI is the method of choice to detect intralabyrinthine tumors. Since endolymphatic hydrops is considered the morphological equivalent of Menière's disease, magnetic resonance imaging including hT2w-FLAIR sequences 4 h after i. v. administration of gadolinium-based contrast agents (GBCA) allows the diagnosis and grading of endolymphatic hydrops in vivo synchronous to diagnosis and monitoring of ILT. To this day, only a few cases of intralabyrinthine schwannoma could be shown to appear simultaneously with endolymphatic hydrops by MRI, but to our knowledge the dedicated distinction of endolymphatic space has not been previously demonstrated. The aim of this work was not only to detect the coincidence of endolymphatic hydrops and vestibular schwannoma, but also to differentiate tumor tissue from endolymphatic space by 3 Tesla MRI. This enables therapy options that are originally indicated for Menière's disease. The aim of this work was to describe the feasibility and usefulness of endolymphatic hydrops MRI on intralabyrinthal tumors in a special case of intravestibular schwannoma to demonstrate the high clinical relevance and impact in therapeutic decision-making for the synchronous appearance of endolymphatic hydrops and intralabyrinthine tumors. Therefore, we present a typical case of Menière's disease in contrast to a patient with an intralabyrinthine schwannoma and Menière-like symptoms.
不同内耳病变同时出现且临床表现几乎相同,如梅尼埃病和前庭神经鞘瘤,这种情况非常罕见,但会给治疗方案带来重大难题。MRI是检测迷路内肿瘤的首选方法。由于内淋巴积水被认为是梅尼埃病的形态学对应表现,静脉注射钆基造影剂(GBCA)4小时后进行包括hT2w-FLAIR序列在内的磁共振成像,能够在体内同步诊断和监测内淋巴积水,同时诊断和分级迷路内肿瘤(ILT)。迄今为止,仅有少数迷路内神经鞘瘤病例经MRI显示与内淋巴积水同时出现,但据我们所知,此前尚未证实对内淋巴间隙的专门区分。这项工作的目的不仅是检测内淋巴积水和前庭神经鞘瘤的巧合情况,还通过3特斯拉MRI将肿瘤组织与内淋巴间隙区分开来。这使得原本适用于梅尼埃病的治疗方案成为可能。这项工作的目的是描述内淋巴积水MRI在一例特殊的前庭内神经鞘瘤迷路内肿瘤中的可行性和实用性,以证明内淋巴积水和迷路内肿瘤同时出现时在治疗决策中的高度临床相关性和影响。因此,我们展示了一例典型的梅尼埃病病例,并与一名有迷路内神经鞘瘤和类似梅尼埃症状的患者进行对比。