Kühn Andrea A, Krause Patricia, Lauritsch Katharina, Zentner Christian, Brücke Christof, Schneider Gerd-Helge
Department of Neurology, Charité-University Medicine, Berlin, Germany
Department of Neurology, Charité-University Medicine, Berlin, Germany.
J Child Neurol. 2014 Nov;29(11):NP149-50. doi: 10.1177/0883073813513071. Epub 2014 Jan 21.
Myoclonus dystonia syndrome is often misdiagnosed in young children and appropriate treatment is delayed, which has a negative impact on motor development, participation, and emotional well-being. In severely affected patients, deep brain stimulation of the globus pallidus internus has been used successfully to treat both dystonia and myoclonus. Here, the authors present a case of early successful treatment of myoclonus dystonia syndrome by pallidal deep brain stimulation in a patient at the age of 17 years leading to 83% reduction in dystonia score and 89% reduction in myoclonus. The patient gained significant improvement in motor function as well as increased participation and reduced stigma.
肌阵挛性肌张力障碍综合征在幼儿中常被误诊，适当治疗被延误，这对运动发育、参与度和情绪健康产生负面影响。在严重受影响的患者中，内侧苍白球的深部脑刺激已成功用于治疗肌张力障碍和肌阵挛。在此，作者介绍了一例17岁患者通过苍白球深部脑刺激早期成功治疗肌阵挛性肌张力障碍综合征的病例，导致肌张力障碍评分降低83%，肌阵挛降低89%。患者的运动功能得到显著改善，参与度增加，耻辱感减轻。
