Wakisaka S, Ichikawa H, Nishikawa S, Matsuo S, Takano Y, Akai M
First Department of Oral Anatomy, Osaka University Faculty of Dentistry, Japan.
Arch Oral Biol. 1987;32(6):449-53. doi: 10.1016/0003-9969(87)90082-3.
The correlation between substance P (SP) and vasoactive intestinal polypeptide (VIP)-containing nerve fibres in the pulp was examined by double immunofluorescence. Both SP- and VIP-containing fibres entered the pulp in bundles with the blood vessels and spread throughout the pulp. In the coronal pulp, both SP- and VIP-containing nerve fibres formed networks on the walls of blood vessels, but both peptide-containing nerve fibres were not observed together in relation to vessels. There were more SP-containing fibres than VIP-containing ones. In the odontoblast layer, there were many SP-containing fibres but few VIP-containing ones.
通过双重免疫荧光法检测了牙髓中P物质（SP）与含血管活性肠肽（VIP）神经纤维之间的相关性。含SP和VIP的纤维均与血管成束进入牙髓，并遍布整个牙髓。在冠髓中，含SP和VIP的神经纤维均在血管壁上形成网络，但未观察到与血管相关的两种含肽神经纤维同时存在。含SP的纤维比含VIP的纤维更多。在成牙本质细胞层，有许多含SP的纤维，但含VIP的纤维很少。
