Komaki Ritsuko, Gomez Daniel R
Department of Radiation Oncology, University of Texas MD Anderson Cancer Center , Houston, TX , USA.
Front Oncol. 2014 Jan 10;3:330. doi: 10.3389/fonc.2013.00330.
Although historically thymoma and thymic carcinoma have been treated surgically, radiation therapy also has an important role, either as postoperative therapy to reduce the risk of mediastinal recurrence or as part of definitive treatment for patients who cannot undergo surgery. Induction chemotherapy and molecular targeted agents may also be appropriate for thymic carcinoma, the behavior of which resembles non-small-cell lung carcinoma more than that of thymoma or invasive thymoma and is increasingly being treated like lung cancer. We present here a review of current therapies for thymic malignancies and briefly discuss the potential benefits from novel technologies for such treatment.
虽然从历史上看胸腺瘤和胸腺癌一直采用手术治疗，但放射治疗也发挥着重要作用，既可以作为术后治疗以降低纵隔复发风险，也可以作为无法接受手术患者的确定性治疗的一部分。诱导化疗和分子靶向药物也可能适用于胸腺癌，其行为更类似于非小细胞肺癌，而不是胸腺瘤或侵袭性胸腺瘤，并且越来越多地像肺癌一样进行治疗。我们在此对胸腺恶性肿瘤的当前治疗方法进行综述，并简要讨论此类治疗新技术的潜在益处。
