Ahmed Adnan, Soin Sarthak, Patel Sabah
Department of Internal Medicine, Presence Saint Joseph Hospital, Chicago, Illinois, USA.
BMJ Case Rep. 2019 Mar 31;12(3):e229136. doi: 10.1136/bcr-2018-229136.
Thymic carcinoma is a rare tumour of the thymus, representing less than 1% of thymic malignancies. It has an annual incidence of 0.15-0.32 per 1 00 000 person-years. It is found incidentally in 30% of the patients as an opacity on chest X-ray or with non-specific complaints of persistent cough, chest pain, fatigue, shortness of breath, arm and facial swelling, and upper airway congestion related to tumour extension. We present the case of a 59-year-old man with a history of Graves' disease status post radiation treatment presenting with cough and left lingual opacity on chest X-ray, confirmed to be thymic carcinoma with pericardial invasion and lymph node metastasis. We aim to discuss the presentation, treatment modalities and outcome associated with this rare tumour.
胸腺癌是一种罕见的胸腺肿瘤，占胸腺恶性肿瘤的比例不到1%。其年发病率为每10万人年0.15 - 0.32例。30%的患者是在胸部X光检查时偶然发现肺部有不透明阴影，或伴有持续咳嗽、胸痛、疲劳、气短、手臂和面部肿胀以及与肿瘤侵犯有关的上呼吸道充血等非特异性症状。我们报告一例59岁男性患者，有格雷夫斯病放疗史，因咳嗽和胸部X光显示左舌叶不透明阴影就诊，确诊为胸腺癌伴心包侵犯和淋巴结转移。我们旨在讨论这种罕见肿瘤的临床表现、治疗方式及预后。
