Danesi M A
Department of Clinical Neurophysiology, National Hospital for Nervous Diseases, Queen Square, London, U.K.
Electroencephalogr Clin Neurophysiol. 1987 Dec;67(6):588-90. doi: 10.1016/0013-4694(87)90062-9.
EEG records of 408 consecutive patients, after a single epileptic seizure, were examined for evidence of a paroxysmal response to photic stimulation (PPD). 6.4% of the patients had PPD, a percentage slightly, but not significantly, higher than the 5.9% found on examining EEG records of 3161 clearly diagnosed epileptic patients who were routinely investigated at the same department over the same period. The observation in this study therefore suggests that a single epileptic seizure in a patient, like clearly established epilepsy, is associated with increased cerebral neuronal excitability as reflected by the PPD.
对408例单次癫痫发作后的连续患者的脑电图记录进行检查，以寻找对光刺激阵发性反应（PPD）的证据。6.4%的患者有PPD，该百分比略高于同期在同一科室常规检查的3161例明确诊断为癫痫患者的脑电图记录中发现的5.9%，但差异无统计学意义。因此，本研究中的观察结果表明，患者的单次癫痫发作，与明确诊断的癫痫一样，与PPD所反映的大脑神经元兴奋性增加有关。
