Flavin Bridget M, Nishida Lynn M, Karbowicz Sean H, Renner Mark E, Leonard Ruth J
RegenceRx, 100 S.W. Market St., M/S 2P, Portland, OR 97207, USA.
J Manag Care Pharm. 2014 Feb;20(2):159-64. doi: 10.18553/jmcp.2014.20.2.159.
Health plans may achieve cost savings by limiting the daily average consumption (DACON) of certain medications and encouraging members and prescribers to select lower cost dosing options. Various strengths of a given medication may be similarly priced per unit; therefore, a single unit of a higher-strength medication may cost less than multiple lower-strength units that provide the same dose. For instance, a single 10 mg tablet may cost less than two 5 mg tablets.
To measure the economic impact of implementing DACON limits for selected medications.
RegenceRx prescription claims data for the top 200 brand and select generic medications from the first quarter of 2011 were searched for DACON limit opportunities. DACON limits were placed on medications that were available in multiple strengths that were similar in cost, and at least one strength was double another (e.g., 5 mg and 10 mg).Phase 1 of the program occurred in December 2011 and consisted of messaging to dispensing pharmacies (either electronic or direct contact). In Phase 2 (effective January 1, 2012), the claims system was coded to prevent payment for prescription claims in quantities exceeding DACON limits ( greater than 1.9 tablets/day). During this phase, dispensing pharmacists received electronic messaging at the point of service recommending a transition to the least costly dosing option. If the dispensing pharmacist determined transition was not clinically appropriate, the pharmacy was able to contact RegenceRx customer service for an override.Impact was determined by analyzing prescription claims for the selected medications for the 3 months following implementation of DACON limits (January-March 2012). Specific measurements analyzed included number of claims not paid because of exceeding DACON limits, health plan administrative burden, and cost avoidance.
DACON limits were placed on 41 medications for commercial lines of business and 35 medications for Medicare Part D lines of business, based on the medication selection criteria (DACON limits were not placed on classes of clinical concern for Medicare Part D). A total of 5,100 claims across both commercial and Medicare Part D lines of business for January to March 2012 were impacted by implementation of DACON limits at the point of service. Duloxetine, niacin CR, and generic temazepam were responsible for more than 60% of the DACON limit claims volume. Implementing DACON limits resulted in a total cost avoidance of approximately $730,000 across both commercial and Medicare Part D lines of business for January to March 2012. Duloxetine, niacin CR, and aripiprazole were responsible for nearly 60% of the total aggregate cost avoidance. After adjustment for health plan administrative costs, the total cost avoidance was just under $720,000.
Implementing DACON limits on selected medications provided a cost avoidance of approximately $720,000 over a 3-month period with limited interruption to patient access and relatively low administrative burden. This reduction could result in annualized savings of nearly $3 million.
健康计划可通过限制某些药物的每日平均消耗量(DACON),并鼓励会员和开处方者选择成本较低的给药方案来实现成本节约。给定药物的不同规格每单位价格可能相近;因此,单单位高规格药物的成本可能低于提供相同剂量的多个低规格单位的成本。例如,一片10毫克的药片可能比两片5毫克的药片成本更低。
衡量对选定药物实施DACON限制的经济影响。
在RegenceRx 2011年第一季度前200种品牌药和选定的仿制药的处方索赔数据中寻找DACON限制机会。对有多种成本相近的规格且至少有一种规格是另一种规格两倍(如5毫克和10毫克)的药物设置DACON限制。该计划的第一阶段于2011年12月进行,包括向配药药房发送信息(通过电子方式或直接联系)。在第二阶段(2012年1月1日起生效),索赔系统进行编码,以防止支付超过DACON限制数量(超过1.9片/天)的处方索赔。在此阶段,配药药剂师在服务点收到电子信息,建议改用成本最低的给药方案。如果配药药剂师确定转换在临床上不合适,药房可以联系RegenceRx客户服务进行豁免。通过分析实施DACON限制后(2012年1月至3月)选定药物的处方索赔来确定影响。分析的具体指标包括因超过DACON限制而未支付的索赔数量、健康计划的行政负担以及成本节约情况。
根据药物选择标准,对商业业务线的41种药物和医疗保险D部分业务线的35种药物设置了DACON限制(医疗保险D部分对临床关注的类别未设置DACON限制)。2012年1月至3月,商业和医疗保险D部分业务线共有5100份索赔因在服务点实施DACON限制而受到影响。度洛西汀、缓释烟酸和通用型替马西泮占DACON限制索赔量的60%以上。2012年1月至3月,对商业和医疗保险D部分业务线实施DACON限制共节约成本约73万美元。度洛西汀、缓释烟酸和阿立哌唑占总节约成本的近60%。在调整健康计划行政成本后,总节约成本略低于72万美元。
对选定药物实施DACON限制在3个月内节约了约72万美元成本,对患者用药的干扰有限,行政负担相对较低。这一成本降低可能带来近300万美元的年化节约。