Scott Amy B, Culley Eric J, O'Donnell Jerry
Highmark BlueShield, Pharmacy Affairs, Pittsburgh, PA 15222, USA.
J Manag Care Pharm. 2007 Jun;13(5):412-9. doi: 10.18553/jmcp.2007.13.5.412.
Greater use of generic drugs, particularly as measured by the generic utilization or dispensing ratio (GDR), is an effective means of managing care by attaining the same clinical outcome as brand drugs but at lower cost. Health plans encourage members to use generic drugs through copayments that are lower than for brand drugs. Encouraging physicians to prescribe generic drugs in therapeutic selection continues to be an opportunity for health plans to produce drug cost savings without compromising safety or efficacy.
To determine if the addition of an automated generic drug sampling system in primary care physician offices would increase (1) the GDR of the sampled therapeutic categories and (2) the overall GDR.
To encourage prescribers to increase their use of generic pharmaceuticals, this managed care organization of 2.3 million members with pharmacy benefits, who represent about two thirds of approximately 3.5 million total health plan members, collaborated with a vendor that developed an automated generic medication sampling intervention that takes place in the physician's office at the point of care. The generic sampling system (kiosk) included 21 distinct generic drugs in 36 variations of dose and strength. To isolate the effect of the generic sampling intervention from the general trend of greater generic drug use, we compared physicians participating in the generic sampling program with all other network physicians. Because formal statistical testing of program outcomes was precluded by incomplete physician data, we performed a descriptive, business-case analysis of the program.
Before implementation of the generic sampling program, the physicians in the intervention group and the comparison group had the same GDR of 47.8%. In the first full year of the intervention in 2005, the 301 physicians participating in the generic sampling program had a GDR of 55.3% compared with 54.1% for all of the other approximately 33,000 network physicians. This absolute 1.2 percentage point difference narrowed to 0.8 points in 2006 (59.9% vs. 59.1%). After subtraction of payments made to the vendor of the generic samples, including all administrative costs, the direct drug cost savings were estimated to be $397,486 in 2005 and $453,545 in 2006. The direct drug cost savings per physician participating in the generic sampling program were estimated at $1,321 in 2005 and $719 in 2006. Members paid no copayment for the generic samples and paid lower copayments throughout the continued use of the generic drugs for chronic conditions such as hypertension.
Physician practices that participated in the generic sampling program demonstrated an increase in the average GDR that was slightly greater than the increase in the comparison group of all other network physicians in each of the 2 measurement years, 2005 and 2006. Direct drug cost savings after subtraction of all administrative costs associated with the generic sampling program were estimated at $1,321 per participating physician in 2005 and $719 per participating physician in 2006. Members benefited from no copayment for the generic drug samples and from lower copayments for continued use of the generic drugs.
更多地使用通用药物,尤其是通过通用药物利用率或配药率(GDR)来衡量,是一种有效的医疗管理手段,能够在获得与品牌药物相同临床疗效的同时降低成本。健康计划通过设置低于品牌药物的自付费用,鼓励会员使用通用药物。鼓励医生在治疗选择中开具通用药物,仍然是健康计划在不影响安全性或疗效的前提下节省药物成本的一个机会。
确定在初级保健医生办公室增加自动化通用药物抽样系统是否会提高(1)抽样治疗类别的GDR以及(2)总体GDR。
为鼓励开处方者增加通用药物的使用,这个拥有230万享有药房福利会员的管理式医疗组织(约占350万总健康计划会员的三分之二)与一家供应商合作,该供应商开发了一种在医生办公室即时护理点进行的自动化通用药物抽样干预措施。通用抽样系统(信息亭)包含21种不同的通用药物,有36种剂量和强度变体。为将通用抽样干预的效果与通用药物使用增加的总体趋势区分开来,我们将参与通用抽样计划的医生与所有其他网络医生进行了比较。由于医生数据不完整,无法对项目结果进行正式的统计检验,因此我们对该项目进行了描述性的商业案例分析。
在通用抽样计划实施前,干预组和对照组医生的GDR均为47.8%。在2005年干预的第一个完整年度,参与通用抽样计划的301名医生的GDR为55.3%,而所有其他约33000名网络医生的GDR为54.1%。这个1.2个百分点的绝对差值在2006年缩小到了0.8个百分点(59.9%对59.1%)。在扣除向通用药物样本供应商支付的款项(包括所有行政成本)后,估计2005年直接药物成本节省为397486美元,2006年为453545美元。参与通用抽样计划的每位医生的直接药物成本节省估计在2005年为1321美元,2006年为719美元。会员无需为通用药物样本支付自付费用,并且在持续使用高血压等慢性病的通用药物时支付的自付费用更低。
参与通用抽样计划的医生诊所表明,在2005年和2006年这两个测量年度中,平均GDR的增幅略大于所有其他网络医生对照组的增幅。扣除与通用抽样计划相关的所有行政成本后的直接药物成本节省估计在2005年为每位参与医生1321美元,2006年为每位参与医生719美元。会员从无需为通用药物样本支付自付费用以及持续使用通用药物时支付较低自付费用中受益。