卵巢储备功能超声标志物在预测体外受精和卵胞浆内单精子注射结局中的作用。
Role of ultrasonographic markers of ovarian reserve in prediction of IVF and ICSI outcome.
作者信息
Shaban Mona Mohamed, Abdel Moety Ghada Abdel Fattah
机构信息
Department of Obstetrics and Gynecology, Faculty of Medicine, Cairo University , Cairo , Egypt.
出版信息
Gynecol Endocrinol. 2014 Apr;30(4):290-3. doi: 10.3109/09513590.2013.875996. Epub 2014 Jan 23.
The aim of the study was to assess correlation of ultrasonographic markers of ovarian reserve and IVF/ICSI outcome. Two-hundred twelve IVF/ICSI patients were included. Upon pituitary suppression confirmation, antral follicle count (AFC), ovarian volume (OV), and ovarian stromal indices [vascularization index (VI), flow index (FI), and vascularization flow index (VFI)] were assessed by three-dimensional (3D) and power Doppler (PD) ultrasound and correlated with the number of mature oocytes retrieved. The number of mature oocytes retrieved correlated strongly with AFC (r = 0.832, p ≤ 0.001) and OV (r = 0.835, p ≤ 0.001), but weakly with VI (r = 0.166, p = 0.016), FI (r = 0.151, p = 0.028), and VFI (r = 0.14, p = 0.041). AFC and OV correlate strongly with the number of mature oocytes retrieved in IVF/ICSI cycles, whereas 3D PD indices of the ovarian stromal vascularity have a weak correlation.
本研究的目的是评估卵巢储备的超声标志物与体外受精/卵胞浆内单精子注射（IVF/ICSI）结局之间的相关性。纳入了212例IVF/ICSI患者。在确认垂体抑制后，通过三维（3D）和能量多普勒（PD）超声评估窦卵泡计数（AFC）、卵巢体积（OV）以及卵巢基质指数[血管化指数（VI）、血流指数（FI）和血管化血流指数（VFI）]，并将其与获取的成熟卵母细胞数量进行相关性分析。获取的成熟卵母细胞数量与AFC（r = 0.832，p≤0.001）和OV（r = 0.835，p≤0.001）密切相关，但与VI（r = 0.166，p = 0.016）、FI（r = 0.151，p = 0.028）和VFI（r = 0.14，p = 0.041）的相关性较弱。AFC和OV与IVF/ICSI周期中获取的成熟卵母细胞数量密切相关，而卵巢基质血管的3D PD指数相关性较弱。
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