Ebrard-Charra S, Reyftmann L, Hédon B, Déchaud H
Service de gynécologie-obstétrique et médecine de la reproduction, CHU Arnaud-de-Villeneuve, 371, avenue du Doyen-Gaston-Giraud, 34295 Montpellier cedex 05, France.
Gynecol Obstet Fertil. 2005 Oct;33(10):762-7. doi: 10.1016/j.gyobfe.2005.06.020.
Evaluate whether ovarian antral follicles number, ovarian volume and ovarian area are predictive of ovarian response.
Prospective cohort analysis of 41 women with normal basal serum FSH concentration, who were undergoing their IVF cycle. The ovarian antral follicle number, the ovarian volume and area were determined by transvaginal ultrasonography on the third menstrual day for 20 women, and after pituitary suppression for 21 women. The main outcome measures are the number of follicles the day of HCG with a diameter >or=14 mm, the number of oocytes retrieved and the number of embryos.
The antral follicle count was significantly correlated to the number of follicles (R=0.7; P<0.001), to the number of oocytes retrieved (R=0.46; P=0.008) and to the number of embryos (R=0.44; P=0.01). The ovarian volume and area was significantly correlated to the number of follicles.
The total antral follicle number on day 3 has a predictive value for favourable IVF outcome. Because this sonographic count is easy, safe and inexpensive it should be performed prior every IVF cycle.
评估卵巢窦卵泡数量、卵巢体积和卵巢面积是否可预测卵巢反应。
对41名基础血清促卵泡生成素浓度正常且正在接受体外受精周期治疗的女性进行前瞻性队列分析。20名女性在月经周期第三天经阴道超声测定卵巢窦卵泡数量、卵巢体积和面积，21名女性在垂体抑制后进行测定。主要观察指标为注射人绒毛膜促性腺激素当天直径≥14mm的卵泡数量、获取的卵母细胞数量和胚胎数量。
窦卵泡计数与卵泡数量显著相关（R = 0.7；P < 0.001），与获取的卵母细胞数量显著相关（R = 0.46；P = 0.008），与胚胎数量显著相关（R = 0.44；P = 0.01）。卵巢体积和面积与卵泡数量显著相关。
第3天的窦卵泡总数对体外受精的良好结局具有预测价值。由于这种超声计数简便、安全且成本低廉，应在每个体外受精周期前进行。
