NIHR Biomedical Research Centre for Ophthalmology, Moorfields Eye Hospital, , London, UK.
Br J Ophthalmol. 2014 Apr;98(4):544-9. doi: 10.1136/bjophthalmol-2013-303559. Epub 2014 Jan 23.
To investigate factors that may influence successful correction of hypotony in a consecutive series of patients with cyclodialysis clefts repaired surgically over a 10-year period.
Retrospective interventional case series.
Interventional case series of consecutive patients with cyclodialysis clefts and hypotony treated surgically after failure of conservative treatment.
Eighteen patients (18 eyes) of mean (SD) age 48.3 (15.8) years at the time of surgery were included (16 male, 2 female). All were diagnosed using gonioscopy, usually assisted with intracameral viscoelastic injection. Imaging used in three cases was not found to be sufficiently precise to plan surgical intervention, without prior gonioscopic cleft visualisation. The intraocular pressure (IOP) was restored in nine cases (50%) after one procedure with a postoperative IOP (mean ± SD) of 13.6 ± 4.5 mm Hg (6/11 who had cyclopexy as a first procedure and 3/6 who had cryopexy). 2-3 procedures were required in the remaining nine patients. There was a trend towards the use of cyclopexy for larger clefts and cryopexy for smaller clefts (NS). We observed a trend for a lower likelihood of successful closure of larger clefts after one intervention. Two eyes that had cyclopexy required later IOP-lowering surgery to achieve IOP control.
Most clefts were closed with one procedure. A trend towards larger cleft size as a preoperative risk factor for failure to achieve closure with one procedure was observed. In this series, imaging was not found to be sufficiently precise to replace viscoelastic-assisted gonioscopy in the diagnosis and evaluation of cyclodialysis clefts.
调查在过去 10 年中接受手术修复的连续系列睫状体脱离裂患者中,可能影响眼压成功矫正的因素。
回顾性干预性病例系列研究。
对手术治疗失败后接受保守治疗的睫状体脱离裂伴低眼压的连续患者进行干预性病例系列研究。
18 例(18 只眼)患者的平均(标准差)年龄为 48.3(15.8)岁,均采用房角镜检查确诊,通常辅助房内黏弹剂注射。3 例病例的影像学检查发现不够精确,无法对手术干预进行规划,术前未发现房角裂。9 例(50%)患者在一次手术后眼压(IOP)恢复正常,术后 IOP(平均值±标准差)为 13.6±4.5mmHg(6/11 例行环扎术作为首次手术,3/6 例行冷冻术)。其余 9 例患者需要 2-3 次手术。对于较大的裂,倾向于使用环扎术,对于较小的裂,倾向于使用冷冻术(无统计学差异)。我们观察到,较大的裂在一次干预后闭合的可能性较低。2 只接受环扎术的眼后来需要眼压降低手术以控制眼压。
大多数裂可以通过一次手术闭合。术前裂较大是一次手术不能成功闭合的一个趋势性危险因素。在本系列中,影像学检查发现其精确性不足以替代黏弹剂辅助房角镜检查用于睫状体脱离裂的诊断和评估。