Quiroga Rodrigo Quian
Centre for Systems Neuroscience, University of Leicester, Leicester, UK,
Acta Neurobiol Exp (Wars). 2013;73(4):463-71. doi: 10.55782/ane-2013-1952.
In this short review, I revise the notion of gnostic cells posited by Konorski, together with similar arguments by James, Lettvin and Barlow--namely, the idea of pontifical, grandmother and cardinal cells, respectively. I then discuss whether the characteristics of the recently discovered concept cells, i.e. neurons in the human medial temporal lobe with a very high degree of specificity and invariance, fit the conjecture of gnostic or grandmother cells and then discuss the key role of concept cells in memory formation.
在这篇简短的综述中，我重新审视了科诺尔斯基提出的认知细胞概念，以及詹姆斯、莱特文和巴洛提出的类似观点，即分别为教皇细胞、祖母细胞和枢机细胞的概念。然后，我讨论了最近发现的概念细胞（即人类内侧颞叶中具有高度特异性和不变性的神经元）的特征是否符合认知细胞或祖母细胞的推测，接着探讨了概念细胞在记忆形成中的关键作用。
