McGrady Michael
Dental Public Health Public Health England/University of Manchester School of Dentistry.
Br Dent J. 2014 Jan;216(2):78-9. doi: 10.1038/sj.bdj.2014.16.
Data on fluoride exposure of infants are sparse. This study aimed to estimate total daily fluoride intake (TDFI) of infants aged 1-12 months, living in non-fluoridated and fluoridated areas in north-east England.
Daily dietary fluoride intake was assessed using a three-day food diary coupled with analysis of fluoride content of food/drink consumed, using a F-ISE and diffusion method. A questionnaire with an interview was used to collect information on toothbrushing habits. TDFI was estimated from diet, plus fluoride supplements and dentifrice ingestion where used.
Thirty-eight infants completed the study; 19 receiving fluoridated water (mean 0.97 mgF/l) and 19 receiving non-fluoridated water (mean 0.19 mgF/l). Mean (SD) TDFI for the infants living in fluoridated and non-fluoridated areas was 0.107 (0.054) and 0.024 (0.015) mg/kg body weight per day, respectively. Diet was the only fluoride source for 87% of infants and none used fluoride supplements. For infants for whom mouth/teeth cleaning was undertaken, dentifrice contribution to TDFI ranged from 24 to 78%.
Infants living in fluoridated areas, in general, may receive a fluoride intake, from diet only, of more than the suggested optimal range for TDFI. This emphasises the importance of estimating TDFI at an individual level when recommendations for fluoride use are being considered.
关于婴儿氟暴露的数据稀少。本研究旨在估算居住在英格兰东北部非氟化和氟化地区的1至12个月婴儿的每日总氟摄入量(TDFI)。
使用为期三天的食物日记,并结合使用氟离子选择电极(F-ISE)和扩散法分析所摄入食物/饮料的氟含量,来评估每日膳食氟摄入量。通过问卷调查和访谈收集刷牙习惯信息。TDFI是根据饮食、氟补充剂(若使用)和牙膏摄入量估算得出的。
38名婴儿完成了研究;19名饮用氟化水(平均0.97mgF/l),19名饮用非氟化水(平均0.19mgF/l)。居住在氟化和非氟化地区的婴儿的平均(标准差)TDFI分别为每天0.107(0.054)和0.024(0.015)mg/kg体重。饮食是87%婴儿的唯一氟来源,且无人使用氟补充剂。对于进行口腔/牙齿清洁的婴儿,牙膏对TDFI的贡献范围为24%至78%。
一般来说,居住在氟化地区的婴儿仅从饮食中摄入的氟可能超过TDFI的建议最佳范围。这强调了在考虑氟使用建议时,在个体层面估算TDFI的重要性。