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妊娠期库欣综合征:一例病例报告及文献综述

Cushing's syndrome in pregnancy: a case report and mini review of the literature.

作者信息

Katulski K, Podfigurna-Stopa A, Maciejewska-Jeske M, Ruchala M, Gurgul E, Szymankiewicz M, Breborowicz G H, Karmelita-Katulska K, Stajgis M, Biczysko M, Gryczynska M, Genazzani A R, Meczekalski B

机构信息

Department of Gynecological Endocrinology .

出版信息

Gynecol Endocrinol. 2014 May;30(5):345-9. doi: 10.3109/09513590.2013.879857. Epub 2014 Jan 24.

Abstract

Adrenal diseases in pregnant women are diagnosed relatively rarely. The main cause of hypercortisolemia during pregnancy is Cushing's syndrome related to adrenal adenoma. It is important to diagnose Cushing's syndrome in pregnant women because it can lead to significant maternal and foetal complications and morbidity. However, due to physiological endocrine changes and symptoms in pregnant women the diagnosis of this disorder can be a challenge. One current case describes a 38-year-old pregnant woman with hypertension, oedema and an adrenal tumour. At the beginning, Conn syndrome was suspected, but after careful analysis Cushing's syndrome (with an adenoma of the right adrenal gland) was diagnosed. After delivery and 5 weeks of pharmacological treatment the patient underwent right side adrenalectomy by laparoscopy.

摘要

孕妇肾上腺疾病的诊断相对少见。孕期皮质醇增多症的主要原因是与肾上腺腺瘤相关的库欣综合征。诊断孕妇的库欣综合征很重要,因为它可导致严重的母婴并发症和发病情况。然而,由于孕妇的生理内分泌变化和症状,这种疾病的诊断可能具有挑战性。当前有一个病例描述了一名38岁的孕妇,伴有高血压、水肿和肾上腺肿瘤。起初怀疑是原发性醛固酮增多症,但经过仔细分析后诊断为库欣综合征(右侧肾上腺腺瘤)。分娩后并经过5周的药物治疗,患者接受了腹腔镜右侧肾上腺切除术。

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