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妊娠期库欣综合征

Cushing's syndrome in pregnancy.

作者信息

Nassi Rossella, Ladu Cristina, Vezzosi Chiara, Mannelli Massimo

机构信息

Endocrinology Unit, San Donato Hospital , Arezzo , Italy and.

出版信息

Gynecol Endocrinol. 2015 Feb;31(2):102-4. doi: 10.3109/09513590.2014.984680. Epub 2014 Nov 28.

Abstract

Cushing's syndrome is a rare condition in the general population and is even less common during pregnancy with only a few cases reported in literature. The diagnosis of Cushing's syndrome may be difficult during pregnancy because the typical features of the disorder and pregnancy may overlap. However, Cushing's syndrome results in increased fetal and maternal complications, and diagnosis and treatment are critical. This report describes a case of 26-year-old female at the 19th week of pregnancy with symptoms and signs of hypercortisolism, where ACTH-independent Cushing's syndrome was diagnosed and treated by robotic laparoscopic adrenalectomy at the 21th week of gestation.

摘要

库欣综合征在普通人群中是一种罕见病症,在孕期更为少见,文献中仅有少数病例报道。孕期诊断库欣综合征可能存在困难,因为该病症的典型特征与孕期表现可能相互重叠。然而,库欣综合征会导致胎儿和母体并发症增加,因此诊断和治疗至关重要。本报告描述了一名26岁女性,在妊娠第19周出现皮质醇增多症的症状和体征,在妊娠第21周被诊断为非促肾上腺皮质激素(ACTH)依赖性库欣综合征,并通过机器人腹腔镜肾上腺切除术进行治疗。

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