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[严重低血容量性休克合并严重肺毛细血管渗漏患者的液体复苏]

[Fluid resuscitation in a patient with severe hypovolemic shock and severe pulmonary capillary leak].

作者信息

Xie Haiting, Li Zhongli, Wu Duobin, Chang Ping, Liu Zhanguo

机构信息

Department of Critical Care Medicine, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, China. E-mail:

出版信息

Nan Fang Yi Ke Da Xue Xue Bao. 2014 Jan;34(1):137-40.

PMID:24463136
Abstract

A male patient undergoing extracorporeal ultrasound lithotripsy developed the symptoms of dyspnea, low blood pressure, palpitations, chest tightness, and sweating, and a clinical diagnosis of pulmonary capillary leak and hypovolemic shock was made. Pulse indicator continuous cardiac output (PiCCO) technique was used for resuscitation according to the measurements of extravascular lung water index (EVLWI) and global end-diastolic volume index (GEDI). The patient showed low levels of cardiac output (CO) and GEDI with a peak EVLWI of 32 ml/kg and profuse pink and thin sputum overflow from the trachea. The high ventilator support parameters failed to correct low oxygen saturation. Restricted fluid infusion was used to reduce pulmonary edema. Colloidal solution was given when GEDI was below 500 ml/m(2), and the volume and fluid infusion rate were reduced for a GEDI higher than 500 ml/m(2). Pulmonary edema was gradually reduced after the treatments with improvement of lactic acid level and liver and kidney functions. Vasopressors were withdrawn 6 days later, mechanical ventilation was discontinued 10 days later, and tracheal intubation was removed 25 days later, after which the patient was discharged. In the treatment of the patient, PiCCO monitoring played an important role.

摘要

一名接受体外超声碎石术的男性患者出现呼吸困难、低血压、心悸、胸闷和出汗症状,临床诊断为肺毛细血管渗漏和低血容量性休克。根据血管外肺水指数(EVLWI)和全心舒张末期容积指数(GEDI)的测量结果,采用脉搏指示连续心输出量(PiCCO)技术进行复苏。患者心输出量(CO)和GEDI水平较低,EVLWI峰值为32 ml/kg,气管有大量粉红色稀薄痰液溢出。高通气支持参数未能纠正低氧饱和度。采用限制液体输注以减轻肺水肿。当GEDI低于500 ml/m²时给予胶体溶液,当GEDI高于500 ml/m²时减少液体量和输注速度。治疗后肺水肿逐渐减轻,乳酸水平及肝肾功能改善。6天后停用血管升压药,10天后停止机械通气,25天后拔除气管插管,随后患者出院。在该患者的治疗中,PiCCO监测发挥了重要作用。

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