Hong Seung Pyo, Park HaeYean, Kwon Jae-Sung, Yoo Eunyoung
Department of Occupational Therapy, Dongnam Health College, Suwon, Republic of Korea.
Department of Occupational Therapy, Florida International University, Miami, FL, USA.
NeuroRehabilitation. 2014;34(3):587-95. doi: 10.3233/NRE-141055.
Eccentric viewing training can be successfully applied in the clinical setting based on positive evidence. Nonetheless, published research should be integrated to provide a conclusive perspective of the efficacy of eccentric viewing training.
Meta-analysis was conducted to examine effectiveness of eccentric viewing training on daily visual activities for individuals with age-related macular degeneration (AMD).
The papers used in this study were located through PubMed, Ovid, ProQuest, EBSCOhost, RISS, and KMbase on studies published between January, 1990 and December, 2012. The keywords for searching were "age-related macular degeneration" and "eccentric viewing", "eccentric fixation", "peripheral vision" or "preferred retinal loci". The effect sizes were calculated using Comprehensive Meta-Analysis 2.0 and interpreted according to Cohen's criteria.
A total of 258 studies were found, among which five papers suited the main selection criteria for final analysis. The entire effect size was 0.660 (95% CI, 0.232 ~ 1.088), indicating a moderate effect size of the eccentric viewing training for individuals with AMD in their daily visual activities (p < 0.05).
The results of this study demonstrated the clinical effectiveness of eccentric viewing training for individuals with AMD. This result should be interpreted cautiously, though, given the possibility of publication bias.
基于确凿的证据，偏心注视训练能够成功应用于临床。然而，已发表的研究应整合起来，以提供关于偏心注视训练疗效的确切观点。
进行荟萃分析，以检验偏心注视训练对年龄相关性黄斑变性（AMD）患者日常视觉活动的有效性。
本研究使用的论文通过PubMed、Ovid、ProQuest、EBSCOhost、RISS和KMbase检索1990年1月至2012年12月发表的研究。检索关键词为“年龄相关性黄斑变性”和“偏心注视”、“偏心固视”、“周边视力”或“最佳视网膜位点”。使用综合荟萃分析2.0计算效应量，并根据科恩标准进行解释。
共检索到258项研究，其中5篇论文符合最终分析的主要入选标准。总体效应量为0.660（95%CI，0.232~1.088），表明偏心注视训练对AMD患者的日常视觉活动有中等效应量（p<0.05）。
本研究结果证明了偏心注视训练对AMD患者的临床有效性。不过，鉴于存在发表偏倚的可能性，对这一结果应谨慎解读。
